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PedAM

Pediatric Disease Annotations & Medicines




Disease vascular disease
Phenotype C0085681|hyperphosphatemia
Sentences 5
PubMedID- 23740131 Background: hyperphosphatemia is associated with cardiovascular disease in patients with chronic kidney disease.
PubMedID- 23364583 Vascular dysfunction characterized by endothelial-cell damage, inflammation, and impaired angiogenesis is described in ckd, and hyperphosphatemia has been associated with vascular disease in ckd and general populations.
PubMedID- 21567407 hyperphosphatemia is associated with ectopic calcification, cardiovascular disease, and increased mortality in patients with chronic kidney disease (ckd).
PubMedID- 20944546 Vascular calcification, which contributes to cardiovascular disease in patients with uremic hyperphosphatemia, is associated with vascular cell expression of osteogenic genes, including bone morphogenetic protein (bmp)-2 and osteopontin (opn).
PubMedID- 25629999 The association between hyperphosphatemia and increased risk of death from cardiovascular disease/vascular calcification has been well established for a long time.

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