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PedAM

Pediatric Disease Annotations & Medicines




Disease vascular disease
Phenotype C0035309|retinopathy
Sentences 11
PubMedID- 24086307 Diabetes mellitus (dm) is characterized by microvascular disease leading to retinopathy, nephropathy and neuropathy but also by macrovascular atherosclerotic complications like coronary heart disease (chd), peripheral arterial disease (pad) and involvement of cerebral arteries resulting in increased morbidity and mortality [1].
PubMedID- 22364391 Most patients with t2dm suffer serious complications due to chronic hyperglycemia, including nephropathy, neuropathy, retinopathy and accelerated development of cardiovascular disease.
PubMedID- 25944537 Since diabetic retinopathy is closely associated with microvascular disease and endothelial dysfunction, the possible influences of hypertension to increase and of sustained physical activity to reduce endothelial dysfunction are discussed.
PubMedID- 21273496 Age, sex, age at diabetes diagnosis, diabetes duration, hba1c levels, hypertension status, proteinuria, bmi, smoking status, heavy smoking, retinopathy severity, and history of cardiovascular disease and neuropathy at baseline were considered potential risk factors.
PubMedID- 22011803 Background: in patients with type 2 diabetes, the presence of retinopathy is associated with increased cardiovascular disease, regardless of known risk factors for vascular disease.
PubMedID- 21629851 Variables associated with adma and diabetic retinopathy including the presence of macrovascular disease were treated as possible confounders in the regression analysis.
PubMedID- 23841986 However, in patients with background retinopathy, irrespective of other vascular disease, progression of retinopathy can be limited by controlling hba1c so, in these patients, a strict hba1c target could be beneficial [25,26].
PubMedID- 21193734 Diabetic retinopathy is part of a systemic vascular disease in which vasoregression is the primary evolutionary process.
PubMedID- 23477744 We investigated two subgroups of type 2 diabetic patients who did not have previous cardiovascular disease: 51 with retinopathy and 56 without retinopathy.
PubMedID- 23316229 On the other hand, although there is a common mechanism of diabetic microvascular disease in retinopathy and nephropathy, diabetic kidney disease in type 2 diabetes mellitus might be influenced by various factors other than hyperglycemia compared to retinopathy.
PubMedID- 24664757 Diabetic retinopathy is one of the hallmark microvascular diseases secondary to diabetes.

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