PedAM
Pediatric Disease Annotations & Medicines
| Disease | vascular disease |
| Phenotype | C0031090|periodontal disease |
| Sentences | 9 |
| PubMedID- 24348618 | That there is a small but significant increase in the risk of cardiovascular disease among patients with periodontal disease at baseline. |
| PubMedID- 25261434 | periodontal diseases are frequently associated with cardiovascular diseases (cvd). |
| PubMedID- 25880326 | periodontal disease is associated with cardiovascular disease and is thought to accelerate systemic atherosclerosis [6]. |
| PubMedID- 26331175 | Estimated the relationship between inflammatory periodontal diseases and the risk of developing cardiovascular disease. |
| PubMedID- 23597063 | periodontal disease is associated with cardiovascular disease in the general population [25] and emerging data suggest a link between periodontitis and mortality in people with chronic kidney disease treated with dialysis [26,27]. |
| PubMedID- 21814546 | Despite the links of periodontal disease with cardiovascular diseases, adverse pregnancy outcomes and diabetes, no meta-analysis of socioeconomic variations in periodontal disease exists. |
| PubMedID- 20575683 | Severe periodontal disease is associated with cardiovascular disease as sequelae of a systemic inflammatory response. |
| PubMedID- 25803052 | Potential mechanisms include inflammatory mediators produced in response to periodontal pathogens[27,28,29,30,31], which produce chronic systemic inflammation and neuropathology; increasing risk of stroke and cerebrovascular disease in those with periodontal disease; dissemination of oral gram negative bacteria to the brain via a transient bacteremia[32,33,34,35]; low intake of nutrients, which could cause tooth loss due to vitamins b deficiency[36] and mercury released from dental amalgam[37]. |
| PubMedID- 26114433 | However, more recent review studies including one by an american heart association (aha) working group analyzed 537 peer-reviewed publications, and concluded that periodontal disease is associated with atherosclerotic vascular disease independent of known confounding factors[19]. |
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