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PedAM

Pediatric Disease Annotations & Medicines




Disease vascular disease
Phenotype C0022116|ischemia
Sentences 27
PubMedID- 24278695 ischemia due to vascular disease impedes healing by reducing the supply of oxygen, nutrients, and soluble mediators that are involved in the repair process [11].
PubMedID- 23653894 Extrinsic factors include repeated trauma or mechanical stress applied to a foot that has been rendered insensitive due to neuropathy as well as ischemia as a result of macro- or microvascular disease [5].
PubMedID- 22865983 The tachyarrhythmias can result in haemodynamic instability causing reduced cerebral perfusion, which can aggravate stroke and may also increase the risk of cardiac ischemia in patients with associated cardiovascular disease.
PubMedID- 24809351 It has become widely accepted that ischemia-related sds are part of the pathophysiology of cerebrovascular diseases and predict worse outcome.
PubMedID- 23514754 Myocardial infarction (mi) is one of the primary cardiovascular diseases which lead to cardiomyocyte ischemia, ventricular hypertrophy, heart failure, and death.
PubMedID- 23888179 Oxygenation via vascularization is essential for the survival of cardiac tissues; both acute and chronic ischemia are associated with cardiovascular disease.
PubMedID- 23762500 There have been comparisons between interstitial myocardial fibrosis in chimpanzees and other great apes, and humans, although the latter tend to develop scarring and fibrosis secondary to vascular disease with infarction and ischemia (1).
PubMedID- 25161970 [2] it has been proposed that submucus vascular embolism,[3] chronic ischemia due to atheromatous vascular disease or arteritis,[4] or drugs such as enteric coated potassium tablets are responsible for them.
PubMedID- 26346540 Heart rate variability, a measure of autonomic dysfunction, has been associated with an increased risk of myocardial ischemia in patients with cardiovascular disease [18].
PubMedID- 22110081 Purpose: because retinal vascular disease is associated with ischemia and increased oxidative stress, the vasodilator function of retinal arterioles was examined after retinal ischemia induced by elevated intraocular pressure (iop).
PubMedID- 21598902 Surgeons should be aware of potential limb threatening ischemia in patients with peripheral vascular disease, especially in those with prior lower extremity bypass grafts.
PubMedID- 24476740 The rationale behind the use of cell-based therapies—besides the presence of macro- and microvascular disease leading to ischemia and hypoxia or hyperglycemia, infection, and inflammatory reactions and so on—is the fact that cells in chronic wounds are phenotypically altered or senescent or both [10,11].
PubMedID- 25252026 Possible mechanisms for cognitive impairment include accelerated cerebrovascular disease with ischemia, subclinical stroke and subcortical atrophy [6–8] mimicking the pattern of age-related cognitive decline.
PubMedID- 24466084 The ca1 subfield of the hippocampus is known to be particularly vulnerable to excitotoxicity resulting from hypoxia and ischemia associated with vascular disease [44], and an animal study using rat model of sivd showed substantially metabolic and histological neurodegeneration in this subfield [45].
PubMedID- 23248777 The ability to predict the occurrence of exercise-induced ischemia in patients with suspected cardiovascular disease was investigated by 1h-nmr blood analysis.
PubMedID- 22287864 These includes patients with active or recent gastrointestinal bleeding, patients with hemorrhagic stroke, and those with hemostatic defects such as severe thrombocytopenia.69 it is contraindicated in patients with evidence of leg ischemia due to peripheral vascular disease.
PubMedID- 23525413 Recent clinical data has led to a new appreciation for the role of the steroid hormone aldosterone (aldo) in the progression and adverse outcomes of atherosclerosis.1 inappropriate aldo elevation is common in rapidly growing populations at risk for cardiovascular disease and is associated with cardiovascular ischemia, yet the underlying molecular mechanisms remain to be completely understood.
PubMedID- 20859545 Absolute contraindications to β-blockers are severe or advanced bradycardia, conduction system disease (sinus node dysfunction and/or high-grade av block), asthma, peripheral vascular disease (pad) with rest ischemia, depression, and overt heart failure (hf).
PubMedID- 25889926 Ecg tracings from the stress test were used to confirm if the patient had ischemia consistent with cardiovascular disease.
PubMedID- 26365595 The lack of sensitive diagnostic marker leads to late diagnosis and a progression of underlying vascular disease associated with chronic renal ischemia, which eventually intensifies the magnitude of dkd damage.
PubMedID- 24023716 The development and growth of capillary and arterial blood vessels is a basic process in embryonic development as well as during physiological and pathophysiological processes in the adult organism, such as the neoplastic tumor growth, inflammation, wound healing and the adaptive response to tissue ischemia due to atherosclerotic vascular disease.
PubMedID- 21957469 [22] that it is possible that coronary microvascular disease with ischemia (inducing metabolic stress) could be involved in the development of af.
PubMedID- 23357661 Background: there is an unmet need for proangiogenic therapeutic molecules for the treatment of tissue ischemia in cardiovascular diseases.
PubMedID- 22880112 “cardiovascular disease” included ischemia, infarction, or embolism in any organ other than the cns (i.e., myocardial infarction and pulmonary embolism).
PubMedID- 25027049 Myocardial ischemia in a patient with peripheral vascular disease, an arteriovenous fistula, and patent coronary artery bypass grafts.
PubMedID- 24782817 One possible explanation for this finding is that all patients have intraprocedural showering of emboli, but older and diabetic patients are more likely to have irreversible ischemia attributable to preexisting microvascular disease.
PubMedID- 25289218 Furthermore, pooled data analysis showed that the postoperative incidence of amputations (0.2%) after a pooled follow-up period of 19.9 ± 14.8 months was significantly reduced compared to the expected incidence of postoperative amputations (10–15%).35 in the diabetic population, amputation of the les is the result of 2 phenomena that may exist independently or coexist: ischemia due to peripheral vascular disease vs loss of protective sensation (which exposes the patient to inadvertent trauma with the subsequent development of ulcerations, soft-tissue infection, and necrosis).

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