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PedAM

Pediatric Disease Annotations & Medicines




Disease vascular disease
Phenotype C0022116|ischaemia
Sentences 2
PubMedID- 26527953 The link between hyperuricemia and hbp is not completely understood, but there are several mechanisms that try to explain it: 1) decreased renal blood flow frequently associated with hbp stimulates urate reabsorption in the proximal tubule; 2) local tissue ischaemia due to microvascular disease is responsible for the release of lactate thus blocking urate secretion in the proximal tubule and increasing ua synthesis.
PubMedID- 25949435 Haemorrhagic acalculous cholecystitis has been reported in haemodialysis patients, and ischaemia due to vascular disease in conjunction with uraemia is the postulated mechanism [9–11].

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