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PedAM

Pediatric Disease Annotations & Medicines




Disease vascular disease
Phenotype C0020598|hypoglycemia
Sentences 3
PubMedID- 23761972 The rationale for using ohas such as sitagliptin is to improve glucose control, thereby reducing the risk of microvascular disease without inducing hypoglycemia or weight gain in patients with type 2 diabetes.
PubMedID- 26370882 Background: to investigate whether a history of prior cardiovascular disease (cvd) is associated with severe hypoglycemia (sh) in patients with type 2 diabetes.
PubMedID- 24465132 Where it remains available, pioglitazone can be considered as monotherapy in patients who cannot tolerate or receive metformin when their baseline a1c is roughly 1.5% or less above their goal, in patients at significant risk for repercussions from hypoglycemia (eg, those with established cardiovascular disease), and in patients where insulin resistance is strongly suspected as a significant contributor to hyperglycemia (eg, those with signs of metabolic syndrome).61 it can be used safely in patients with significant renal impairment if that were the contraindication for metformin use.

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