PedAM
Pediatric Disease Annotations & Medicines
| Disease | vascular disease |
| Phenotype | C0020443|hypercholesterolemia |
| Sentences | 26 |
| PubMedID- 26256279 | Evaluation of the potential role of alirocumab in the management of hypercholesterolemia in patients with high-risk cardiovascular disease. |
| PubMedID- 24527446 | hypercholesterolemia, a strong predictor of cardiovascular disease, causes endothelial damage, and the loss of physiological vasomotor activity that results from endothelial damage may become manifested as increased blood pressure (bp) [2]. |
| PubMedID- 25933205 | Subclinical hypothyroidism (sch), which is characterized by normal thyroid hormone levels and elevated tsh levels, is often accompanied by hypercholesterolemia and associated with cardiovascular disease [7]. |
| PubMedID- 23355893 | Decreased hl may contribute to increased cardiovascular disease in patients with isolated hypercholesterolemia, but with normal triglyceride levels and buoyant ldl particles. |
| PubMedID- 26177390 | From these predictors a clinical model was developed (in part based on their availability at presentation) using the following predictors: patient history (age, sex, previous myocardial infarction, pci or coronary artery bypass graft (cabg)), cardiovascular risk factors (hypertension, hypercholesterolemia, family history of cardiovascular disease (cvd), smoking, diabetes mellitus) and ecg findings. |
| PubMedID- 25525746 | We investigated whether anxa5 genetic variations and plasma anxa5 levels were associated with carotid atherosclerosis and contributed to cardiovascular disease (cvd) risk in patients with familial hypercholesterolemia (fh). |
| PubMedID- 26285608 | Elevated concentration of any or all types of lipids in the plasma including hypertriglyceridemia and hypercholesterolemia leads to atherosclerotic cardiovascular disease. |
| PubMedID- 24843520 | Aims/introduction: to evaluate the relationship between fasting plasma glucose (fpg) level and cardiovascular disease in patients with hypercholesterolemia, and to evaluate the effect of pravastatin on risk reduction in a post-hoc analysis of the large-scale management of elevated cholesterol in the primary prevention group of adult japanese (mega) study. |
| PubMedID- 23882283 | Familial hypercholesterolemia (fh) is associated with premature atherosclerotic cardiovascular diseases, and is inherited as an autosomal dominant trait. |
| PubMedID- 23566063 | In conclusion, studied kiwifruit 'hayward' can be a very good ingredient of the diet, especially for patients suffering from hypercholesterolemia and with other cardiovascular diseases, but not for diabetic patients. |
| PubMedID- 24353428 | Simvastatin, atorvastatin and rosuvastatin that were approved for five indications, namely for primary, mixed and familial hypercholesterolemia and for prophylaxis of cardiovascular disease (cvd) in patients with or without previous cvds, mixed hypercholesterolemia scored full marks out of 100 for this criterion. |
| PubMedID- 21733183 | hypercholesterolemia); 2) patients with cardiovascular disease, but without diabetes or lipid disorders; 3) patients without cardiovascular disease, but with diabetes or lipid disorders; and 4) patients with neither cardiovascular disease nor diabetes or lipid disorders (primary prevention). |
| PubMedID- 22230643 | Obesity is a central contributor to cardiovascular disease, being associated with hypertension, hypercholesterolemia, and coronary heart disease [3]. |
| PubMedID- 26558824 | Questionnaires about hypertension, diabetes, hypercholesterolemia, family history of early-onset cardiovascular disease, smoking, alcohol consumption, and sedentary lifestyle were administered. |
| PubMedID- 22247606 | vascular diseases associated with hypercholesterolemia, diabetes and hypertension are characterized by endothelial dysfunction and reduced endothelium-mediated vasodilation. |
| PubMedID- 26510920 | Our finding suggest for the significant association between the presence of cardiovascular disease with hypercholesterolemia and high ldl cholesterol in ckd patients. |
| PubMedID- 20169164 | Background: the risk of premature cardiovascular disease in patients with familial hypercholesterolemia (fh) can be profoundly reduced by cholesterol-lowering therapy, and current guidelines for fh advocate ambitious low-density lipoprotein cholesterol (ldl-c) goals. |
| PubMedID- 21826528 | Elevated ldl cholesterol (ldl-c) promotes atherosclerosis, and it is well established that reducing ldl-c helps to mitigate the risk of developing cardiovascular disease in patients with hypercholesterolemia [1–7]. |
| PubMedID- 23083223 | Cationic hydroxyethyl cellulose (chec) was supplemented in a high-fat diet to determine if this new soluble fiber had an effect on hypercholesterolemia and dyslipidemia associated with cardiovascular disease using golden syrian hamster as an animal model. |
| PubMedID- 22214704 | The individuals with hypertension or hypercholesterolemia were free of any other cardiovascular disease risk factor and were not on any therapy prior to entering the study. |
| PubMedID- 22854495 | Despite effective treatments for several established cardiovascular risk factors, such as hypertension and hypercholesterolemia, the incidence of cardiovascular disease is predicted to increases as the population ages. |
| PubMedID- 23762316 | Because of the importance of oxidant stress in cardiovascular disease processes arising from hypercholesterolemia, we measured superoxide levels in the aortic valves of la mice. |
| PubMedID- 25446106 | hypercholesterolemia may lead to obesity and cardiovascular diseases. |
| PubMedID- 23757599 | Previous studies have reported that cimt is increased in children at high risk for cardiovascular disease because of familial hypercholesterolemia, type 1 diabetes, having parents with premature myocardial infarction, or elevated levels of ultrasensitive c-reactive protein compared with other children (jarvisalo et al. |
| PubMedID- 22309488 | Other studies have found associations with cardiovascular disease in patients with hypercholesterolemia, suggesting that the control of hba1c, independently of lipid management, is necessary in order to reduce the cardiovascular risk particularly in diabetic patients with elevated hba1c [29]. |
| PubMedID- 19880586 | Despite the prevalence of endothelial dysfunction in diabetes and evidence that walnut consumption may improve both endothelial function and biomarkers of cardiovascular disease risk in patients with hypercholesterolemia, no studies have investigated the effect of walnut intake on endothelial function in type 2 diabetes. |
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