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PedAM

Pediatric Disease Annotations & Medicines




Disease vascular disease
Phenotype C0020443|hypercholesterolaemia
Sentences 2
PubMedID- 25885788 Bmd tertiles: 1 <1.067, 3 >1.183 mg/cm2.table 4odds ratio for carotid plaque in relation to bone mineral density (bmd) in systemic lupus erythematosus (sle) patients compared with matched controlsunadjusted modelsp-valuemultivariate adjusted modelsp-valuepostmenopausal* adjusted modelsp-valueodds ratio (95% ci)odds ratio (95% ci)odds ratio (95% ci)bmdtotal body2.11 (1.20, 3.72)0.0101.77 (0.96, 3.24)0.0662.62 (1.10, 6.24)0.030lumbar spine, vertebrae l1 to l42.08 (1.18, 3.66)0.0111.75 (0.96, 3.21)0.0702.59 (1.08, 6.19)0.032total hip2.00 (1.14, 3.52)0.0161.74 (0.95, 3.18)0.0742.71 (1.13, 6.52)0.026femoral neck2.06 (1.17, 3.63)0.0131.76 (0.96, 3.22)0.0672.72 (1.14, 6.46)0.024t-scoretotal body2.12 (1.20, 3.74)0.0101.78 (0.97, 3.26)0.0642.63 (1.10, 6.26)0.029lumbar spine, vertebrae l1 to l42.11 (1.20, 3.72)0.0091.78 (0.97, 3.26)0.0622.66 (1.12, 6.33)0.027total hip1.98 (1.13, 3.49)0.0181.72 (0.94, 3.15)0.0792.69 (1.12, 6.46)0.027femoral neck2.02 (1.14, 3.56)0.0161.74 (0.95, 3.19)0.0732.73 (1.15, 6.51)0.023who osteoporosislow bmd, lumbar spine2.17 (1.23, 3.82)0.0081.73 (0.94, 3.19)0.0802.63 (1.09, 6.32)0.031low bmd, total hip1.98 (1.12, 3.49)0.0181.70 (0.93, 3.12)0.0852.75 (1.15, 6.58)0.023low bmd, femoral neck2.00 (1.13, 3.54)0.0171.72 (0.94, 3.16)0.0792.74 (1.15, 6.55)0.024low bmd, at least one region2.08 (1.19, 3.64)0.0101.78 (0.97, 3.24)0.0622.71 (1.14, 6.46)0.024multivariate models were adjusted for hypertension, hypercholesterolaemia and history of cardiovascular disease.
PubMedID- 25599690 hypercholesterolaemia is one of the main cardiovascular disease risk factors (cdrfs) and, according to different studies undertaken in spain, its prevalence in terms of total plasma cholesterol concentrations of over 250 mg/dl, extends to 20%-23% of the adult population [1, 2].

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