PedAM
Pediatric Disease Annotations & Medicines
| Disease | vascular disease |
| Phenotype | C0011847|diabetes |
| Sentences | 529 |
| PubMedID- 23049260 | Jablecka et al treated 38 patients who had peripheral vascular disease with type ii diabetes using l-arginine.26 the total study population was 50 (38 subjects and twelve controls). |
| PubMedID- 21253508 | Although the results of the recent action to control cardiovascular disease in diabetes (accord) trial did not report side effects associated with the use of the fibrate class of ppar α agonists [17], other studies have reported that they can increase the risk for myopathy, cholelithiasis, and venous thrombosis [18]. |
| PubMedID- 24757198 | All patients had insulin-treated type 2 diabetes and a history of either cardiovascular disease or two cardiovascular risk factors. |
| PubMedID- 20350283 | Despite the profound clinical importance of vascular disease in patients with diabetes mellitus, our understanding of the molecular and cellular mechanisms by which diabetes promotes these vascular complications is incomplete. |
| PubMedID- 23738569 | Data were recorded on hypertension, diabetes, a history of cerebral vascular disease and other chronic diseases. |
| PubMedID- 25109981 | Although there is substantial evidence linking diabetes with cardiovascular disease, the specific effect of hyper- (or hypo-) glycaemia is less well understood. |
| PubMedID- 22474525 | A therapeutic effect of myricetin in patients with cardiovascular diseases associated with diabetes mellitus has also been reported [4, 5]. |
| PubMedID- 26029318 | Further studies addressing the mechanisms responsible for sex differences in the excess risk of cardiovascular diseases associated with diabetes are needed to improve the prevention and management of diabetes in clinical practise. |
| PubMedID- 23251156 | The increase in vascular disease in patients with diabetes is thought to be due to the deleterious effects of metabolic abnormalities, such as hyperglycemia, insulin resistance, dyslipidemia, and advanced glycation end products [18, 19]. |
| PubMedID- 25899452 | Statins have been shown to be beneficial in reducing cardiovascular disease (cvd) in patients with type 2 diabetes [1, 2], but it remains unclear whether these effects can be explained by their lipid-lowering effects only. |
| PubMedID- 20847892 | Evidence suggests that the maintenance of a large muscle mass may reduce metabolic risk factors—namely, obesity, dyslipidaemia, and type 2 diabetes mellitus—associated with cardiovascular disease [13–15]. |
| PubMedID- 23451184 | To date, growing clinical evidence indicates that nafld is linked to an increased risk of cardiovascular disease (cvd) both in patients without diabetes and in those with type 2 diabetes [3], [4]. |
| PubMedID- 23217598 | The prevalence of stroke and cvd decreased gradually (p for trend 0.025 and <0.001, respectively), while the prevalence of peripheral vascular disease (pvd) increased in patients with diabetes during the study period (p for trend <0.001). |
| PubMedID- 24686885 | Among those with established diabetes, the risk of cardiovascular disease (cvd) and mortality can be reduced by intensive treatment of single risk factors, including blood pressure, cholesterol, and glucose.3–6 further, a small (n = 160) trial of multifactorial treatment found a protective effect at 13 years.7 screen-detected populations have a cvd risk profile that is distinct from that of individuals with clinically diagnosed or established diabetes,8,9 and evidence to inform the treatment of individuals found earlier in the course of the disease, where cvd risk varies greatly,8 is lacking. |
| PubMedID- 25784087 | Association of parental history of diabetes with cardiovascular disease risk factors in children with type 2 diabetes. |
| PubMedID- 22285702 | Risk of elevated resting heart rate on the development of type 2 diabetes in patients with clinically manifest vascular diseases. |
| PubMedID- 22994940 | Our empirical strategy starts with a basic model construct (model 1) that uses control variables such as age, sex, previously diagnosed disease, and health problems (diabetes mellitus, risk of vascular disease, vascular disease, musculoskeletal disease, digestive disease, mental illness, other diseases, and report of an accident in the last 12 months). |
| PubMedID- 20580779 | Our results suggested that incorporation of almonds into a healthy diet has beneficial effects on adiposity, glycemic control, and the lipid profile, thereby potentially decreasing the risk for cardiovascular disease in patients with type 2 diabetes mellitus. |
| PubMedID- 22719800 | Cardiovascular disease in diabetes is linked to increased risk of atherosclerosis, increased levels of triglyceride-rich lipoproteins and enhances hepatic lipogenesis. |
| PubMedID- 19918016 | The value of low-dose aspirin as primary prevention for cardiovascular disease (cvd) in patients with type 2 diabetes remains to be established. |
| PubMedID- 20047771 | Leisure-time physical activity and risk of type 2 diabetes in patients with established vascular disease or poorly controlled vascular risk factors. |
| PubMedID- 26216409 | Despite the strong association with hyperglycaemia, several intervention trials looking at intensive glucose control failed to show reduction of macrovascular disease in patients with diabetes [7]. |
| PubMedID- 21990060 | [cardiovascular disease patients with diabetes mellitus type 2]. |
| PubMedID- 21525440 | Hypertension is a leading risk factor for mortality in both developing and developed countries (1) and a well established risk factor for cardiovascular disease (cvd) in patients with diabetes (2). |
| PubMedID- 20431798 | As a strong relationship exists between all forms of vascular disease in patients with diabetes and hyperlipidemia, it is important to screen for and treat these lipid abnormalities. |
| PubMedID- 25856787 | Data obtained from epidemiological studies have clearly demonstrated that diabetic retinopathy (dr), a common chronic microvascular complication of diabetes, is associated with macrovascular disease [1] as well as with increased cv morbidity and mortality in patients with type 2 diabetes mellitus (t2d) [2]. |
| PubMedID- 25823004 | After adjustment for clinical covariables (age, crp, diabetes and a history of cardiovascular disease) both stnfrs remained independently associated to outcomes (hr: stnfr1: 1.51, 95% ci: 1.30-1.77; stnfr2: 1.13, 95% ci: 1.06-1.20). |
| PubMedID- 24089540 | In obese patients with type 2 diabetes and high risk of cardiovascular disease, monotherapy with metformin or diet-only treatment was associated with lower risk of cardiovascular events than treatment with insulin. |
| PubMedID- 20500877 | An inverse association between weight and adiponectin level has been found [22] and low plasma-adiponectin levels are considered to be a predictor of cardiovascular disease in patients with type 2 diabetes [23]. |
| PubMedID- 19889870 | The presence of vascular disease at baseline in patients with diabetes was additive. |
| PubMedID- 22291824 | We assessed the long-term effects of multifactorial intervention on lfts and their association with cardiovascular disease (cvd) events in patients with mets without diabetes mellitus or cvd. |
| PubMedID- 20431592 | We aimed this study to test the hypotheses that heart rate (hr) variability, evaluated by ambulatory blood pressure monitoring (abpm), predicts risk of incident cardiovascular disease (cvd) in patients with type 2 diabetes (t2dm). |
| PubMedID- 20948832 | Other factors implicated in maldevelopment of the uteroplacental vascular connection include inherited thrombophilias and type i diabetes with vascular disease [3,12]. |
| PubMedID- 22164268 | Although observational studies have reported a strong association between hyperglycemia and increased risk for cardiovascular disease in individuals with type 2 diabetes, the results of recent interventional randomized controlled trials in establishing the benefit of intensive glycemic control on cardiovascular outcomes have been elusive [19]–[22]. |
| PubMedID- 23238663 | Dietary interventions that could reduce the risk of development of cardiovascular disease (cvd) in patients with type 2 diabetes mellitus (t2dm) would clearly be advantageous instead of expensive pharmacological treatments. |
| PubMedID- 26339493 | From regression analysis, we found that diabetes, a history of cardiovascular disease and symptoms of shortness of breath determined hrqol (euroqol) more strongly in men than in women. |
| PubMedID- 24742197 | Second, we included other potential confounding factors, that is, smoking status (never a smoker, former smoker, current smoker), alcohol consumption (non-drinker and current light to moderate drinker (1 to 6 times/week), current heavy drinker (every day)), systolic blood pressure (mmhg), antihypertensive medication use (no, yes), body mass index (kg/m2), diabetes (no, yes), history of cardiovascular disease (no, yes), hdl cholesterol (mg/dl), tg (mg/dl), ast (iu/l), and γgtp (iu/l). |
| PubMedID- 23326760 | In this trial 11 140 patients with type 2 diabetes and a history of macrovascular disease or another risk factor were randomly assigned to intensive glucose control (target <6.5%) or standard glucose control (target hba1c >7%). |
| PubMedID- 24252984 | On the other hand no meaningful relationship was detected between diabetes, history of cerebral vascular diseases, peripheral vascular diseases, myocardial infarction, development of pneumonia following surgery, and laboratory levels of sodium, potassium, glucose, and complete blood cell count (cbc) including white blood cells, red blood cells, platelets in the blood-hemoglobin and hematocrits. |
| PubMedID- 23284911 | Thus, therapeutic inhibition and prevention of microvascular diseases associated with diabetes could be addressed using apoedp to inhibit heparanase activation. |
| PubMedID- 20210989 | In a more recent controlled study performed in our center [6], it was found that blood flow alterations (stenoses and/or occlusions) demonstrated in temporal arteries with doppler ultrasonography are neither specific nor sensitive for gca, since these findings were equally common among elderly individuals or patients with macrovascular disease associated with diabetes mellitus or stroke, due to the temporal artery atherosclerotic changes. |
| PubMedID- 21617108 | Longer follow-up documented a significant reduction in cardiovascular disease in patients with type 1 diabetes treated with intensive glycemic control (45). |
| PubMedID- 23323191 | The pathophysiology underlying cognitive change in type 2 diabetes is examined with reference to vascular disease, hypoglycaemia, inflammation and insulin levels. |
| PubMedID- 23621920 | Helius focuses on three of the major causes of the global burden of disease: cardiovascular disease (including diabetes), mental health (in particular, depressive disorders and substance use disorders), and infectious diseases. |
| PubMedID- 26542673 | There is compelling observational evidence that higher levels of physical activity and cardio-respiratory fitness confers a substantial protection against mortality and premature cardiovascular disease in individuals with diabetes [12]. |
| PubMedID- 25790898 | Cardiovascular disease among women with and without diabetes mellitus and bilateral oophorectomy. |
| PubMedID- 21926285 | diabetes is associated with microvascular disease, white matter hyperintensities (wmhs), cerebral atrophy (1,2), and functional decline (3,4). |
| PubMedID- 25990316 | vascular disease in diabetes mellitus. |
| PubMedID- 24349248 | As described above, the decrease of serum bfgf appears in infarction, stroke and peripheral vascular disease associated with diabetes [16]. |
| PubMedID- 21998600 | Higher vascular calcification scores were related to older age, diabetes, history of cardiovascular disease (cvd), and lower levels of 25(oh)d5). |