PedAM
Pediatric Disease Annotations & Medicines
| Disease | vascular disease |
| Phenotype | C0010068|coronary artery disease |
| Sentences | 27 |
| PubMedID- 22386722 | Introduction: coronary artery disease (cad) is one of the most common cardiovascular diseases and is a major cause of morbidity and mortality worldwide. |
| PubMedID- 21349201 | Cardiovascular diseases, including coronary artery disease (cad), are the major causes of morbidity and cardiovascular death in patients with type 2 diabetes mellitus (t2dm) [1,2]. |
| PubMedID- 21270275 | Cardiovascular disease leading to coronary artery disease and stroke remains the most frequent cause of death in patients with diabetes mellitus, whereas impaired perfusion of the extremities leads to foot ulcers and amputations resulting in high morbidity and subsequent socioeconomic burden (1). |
| PubMedID- 21330644 | To date, the major type of cvd in africans is cerebrovascular disease, with coronary artery disease being uncommon (12). |
| PubMedID- 21035578 | There is also strong evidence that blood pressure targets for populations at high risk of cardiovascular disease, including those with diabetes, coronary artery disease, and chronic kidney disease, should be lower than 140/90 mm hg. |
| PubMedID- 24372467 | Background: previous studies demonstrated the prognostic importance of concomitant polyvascular disease in patients with coronary artery disease (cad). |
| PubMedID- 23274712 | vascular diseases, including coronary artery disease, are the leading cause of death in developed countries. |
| PubMedID- 23829275 | Diabetes is associated with several cardiovascular risk factors, such as abnormal glycemia, lipidemia, visceral obesity, and oxidative stress, which impair endothelial function and predispose patients to macrovascular disease, including coronary artery disease and cerebral vascular disease, ultimately the major causes of morbidity and mortality in diabetic patients [2]. |
| PubMedID- 23223728 | A family history of cardiovascular disease was associated with coronary artery disease and infarction. |
| PubMedID- 20702510 | Objective: to investigate the long-term effect of expanded cardiac rehabilitation on a composite end-point, consisting of cardiovascular death, myocardial infarction or readmission for cardiovascular disease, in patients with coronary artery disease. |
| PubMedID- 25337776 | (6) previous studies have shown increased prevalence of renovascular disease in patients with coronary artery disease,(7-9) in whom renal insufficiency is the main clinical predictor of renal artery stenosis. |
| PubMedID- 25233041 | Retinol-binding protein 4 as a novel risk factor for cardiovascular disease in patients with coronary artery disease and hyperinsulinemia. |
| PubMedID- 20184534 | Background: circulating concentrations of matrix metalloproteinase 9 (mmp-9) are associated with cardiovascular disease mortality in patients with coronary artery disease. |
| PubMedID- 24583313 | With a significant impact on health care, 50-80% of people with diabetes die of cardiovascular disease (including coronary artery disease, stroke, peripheral vascular disease and other vascular disease), making it the major cause of morbidity and mortality in diabetic patients. |
| PubMedID- 22989092 | Drugs that are currently available for lowering blood lipids reduced the coronary artery disease mortality of 23% and cardiovascular disease mortality of 19% in patients with dyslipidemia[4]. |
| PubMedID- 23413209 | Hypertension is considered a risk factor for many cardiovascular diseases, including coronary artery disease, myocardial infarction, arrhythmias, left ventricular hypertrophy, chronic heart failure, and hypertensive cardiomyopathy, all of which emphasize the need to screen patients and start therapy at an early stage in the disease. |
| PubMedID- 24040204 | While these studies suggest that trail can promote atherogenesis and vascular disease, serum concentrations in patients with coronary artery disease (cad) have demonstrated lower trail levels inversely associated with the severity of cad, and especially lower levels in patients with acute coronary syndromes, suggesting a protective role in cardiovascular diseases [44], [52]. |
| PubMedID- 20670400 | Dunn et al[29] found no association between hfe polymorphisms and cardio-vascular disease mortality in patients with coronary artery disease. |
| PubMedID- 26257740 | coronary artery disease (cad) as part of the cardiovascular diseases is a pathology caused by atherosclerosis, a chronic inflammatory disease of the vessel wall characterized by a massive invasion of lipids and inflammatory cells into the inner vessel layer (intima) leading to the formation of atherosclerotic lesions; their constant growth may cause complications such as flow-limiting stenosis and plaque rupture, the latter triggering vessel occlusion through thrombus formation. |
| PubMedID- 25756522 | Cardiovascular disease, including coronary artery disease (cad) and cerebrovascular disease (cvd), is common in the general population, especially in adults past the age of 60 years. |
| PubMedID- 21544978 | Cardiovascular diseases including coronary artery disease and its complications--acute coronary syndromes (acs) are the leading causes of mortality in developed countries. |
| PubMedID- 22210593 | A 77-year-old woman with severe aortic stenosis, severe coronary artery disease, an ejection fraction of 20%, severe peripheral vascular disease, and other comorbidities presented to a private, tertiary referral hospital with shortness of breath that had been worsening over 2 weeks. |
| PubMedID- 23549283 | Cardiovascular and cerebrovascular diseases, encompassing coronary artery disease, heart failure, acute myocardial infarction, arrhythmias et al., are the most common causes of morbidity and mortality in the world [1]. |
| PubMedID- 23277071 | It is well known that osas is a frequent comorbidity as well as a relevant risk factor for cardiovascular diseases (cvd), especially in patients with hypertension, coronary artery disease (cad), arrhythmias, and heart failure. |
| PubMedID- 26316667 | Patients will be excluded if they have any of the following: cardiovascular disease with ongoing symptoms, coronary artery disease with or without revascularization, untreated severe valvular heart disease, untreated arrhythmia; cerebrovascular disease; peripheral vascular disease with ongoing ischaemic symptoms, critical arterial stenosis, gangrene, non-healing ulcer or aneurysm; history of malignancy; human immunodeficiency virus infection; active hepatitis c with detectable viraemia, chronic active hepatitis or liver cirrhosis; any active infection that has not resolved or tuberculosis within the last 6 months; severe chronic lung disease; active inflammatory gastrointestinal disease; active systemic lupus erythematosus; active psychiatric issues; history of non-compliance within the last 6 months. |
| PubMedID- 24625655 | Renal and overall outcomes were compared among atherosclerotic renovascular disease patients with coronary artery disease (arvd-c, n = 75) and without coronary artery disease (arvd, n = 56), within 1 year from initial revascularization and included blood pressure control, renal function, and incident cardiovascular/cerebrovascular events. |
| PubMedID- 21450560 | The risk-benefit ratio may differ in relation to the individual's age, fitness level, and presence of cardiovascular disease; sedentary individuals with underlying coronary artery disease are at greatest risk. |
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