PedAM
Pediatric Disease Annotations & Medicines
| Disease | varicocele |
| Phenotype | C0021359|infertile |
| Sentences | 72 |
| PubMedID- 22162682 | Assessed the rate of chromatin condensation using aniline-blue staining in infertile men with varicocele and showed significant improvement following surgical correction of grade iii varicose veins [31]. |
| PubMedID- 24635706 | This study aimed to assess seminal plasma oxytocin (ot) and oxidative stress (os) levels in infertile men with varicocele (vx). |
| PubMedID- 24976820 | This study included eighty two iranian infertile men with varicocele and eighty healthy donors with proven fertility and normal spermogram at the time of study, as control group. |
| PubMedID- 22022494 | It is suggested that an infertile man with varicocele might have testicular damage reflected by abnormal histologic patterns, such as maturation arrest, before becoming azoospermic [53]. |
| PubMedID- 23493802 | The mean age of infertile men with varicocele and normal controls was (mean±sd) 31.58±6.16, 31.26±5.31 respectively (p=0.8204). |
| PubMedID- 21292253 | Result(s): the mean percentage of aniline blue-stained sperm heads was significantly higher in infertile men with varicocele compared with fertile controls. |
| PubMedID- 24749119 | We report the first case of azoospermia after surgery in a young infertile male patient with left-sided varicocele and severe oligozoospermia undergoing laparoscopic varicocelectomy. |
| PubMedID- 25890347 | Methods: spermatozoa from infertile men with unilateral varicocele (n=5) and from fertile men (control; n=5) were pooled in two groups respectively. |
| PubMedID- 25677140 | Apart from the gstt1 polymorphisms, there are some gene polymorphisms in other phase 2 drug-metabolizing enzymes that have shown potential as markers for the selection of infertile male patients with varicocele to undergo varicocelectomy.910 however, more prospective cohort studies and large-scale randomized trials are needed to further evaluate all these potential markers. |
| PubMedID- 24712000 | These results support that microsurgical repair must be considered as a treatment option in infertile men with palpable varicocele, since improvement in dfi is clearly shown to be associated with higher pregnancy rates (spontaneous or with assisted reproductive technique) [11, 15]. |
| PubMedID- 21188073 | Serum and seminal plasma obtained from 68 (34%) infertile males with varicocele and 82 (41%) without varicocele, and 50 (25%) fertile control males were investigated for the possible relations between fructose levels, steroid hormones, and autoimmunity to sperm antigens. |
| PubMedID- 23159014 | infertile men with varicocele were shown to have the highest percentage of sperm presenting with erc. |
| PubMedID- 20495699 | The relationship between ros levels and the clinical characteristics of infertile men with a varicocele was significantly stronger for samples taken from the isv than for those taken from the peripheral venous blood. |
| PubMedID- 22234009 | Materials and methods: the medical records of 183 infertile patients with clinical varicocele were retrospectively reviewed. |
| PubMedID- 25246910 | Materials and methods: 113 infertile men with varicocele were divided into four groups. |
| PubMedID- 25405715 | The aim of the present study was to investigate the pufa composition in spermatozoa of infertile men with varicocele and to evaluate the potential relationship between pufa and varicocele. |
| PubMedID- 23373534 | The concentration of no in infertile patients with varicocele, and its correlation with the sperm fertility test named the hypo-osmotic swelling (hos) test for sperm membranes and semen analysis, was also examined. |
| PubMedID- 19062002 | Result(s): statistically significant differences in dna damage repair-associated proteins and apoptosis markers were observed in infertile men with varicocele compared with fertile young men. |
| PubMedID- 25168538 | Objective: to assess seminal bax and bcl2 gene and protein expressions in infertile men with varicocele (vx). |
| PubMedID- 21993123 | Re: sperm chromatin condensation in infertile men with varicocele before and after surgical repair. |
| PubMedID- 25733269 | Objective: to compare the sperm protein profile between infertile men with unilateral varicocele and infertile men with bilateral varicocele. |
| PubMedID- 26342542 | Among infertile adults with a varicocele, surgery is indicated in the presence of abnormal semen analysis regardless of testicular atrophy. |
| PubMedID- 21868008 | Result(s): sperm caspase-9 was significantly increased in infertile oat men associated with varicocele compared with oat men without varicocele and healthy fertile control subjects. |
| PubMedID- 21615451 | In total, 124 consecutive male subjects were divided into the following groups: healthy fertile controls (n = 10), gp1 (n = 28); infertile males with subclinical varicocele, gp2 (n = 26); infertile males with grade i left varicocele, gp3 (n = 28); infertile males with grade ii left varicocele and gp4 (n = 32); infertile males with grade iii left varicocele. |
| PubMedID- 24967335 | In this study, multiple dna fragmentation analyses (tunel, scd, and scsa) were performed on semen samples from sixty infertile patients with varicocele (15 clinical varicoceles, 19 clinical varicoceles after surgical treatment, 16 subclinical varicoceles, and 10 subclinical varicoceles after surgical treatment). |
| PubMedID- 24183580 | Treatment is likely to be effective in infertile men with clinical varicocele and impaired spermatogenesis. |
| PubMedID- 24207161 | Methods: we prospectively analyzed 5 infertile men with ncs-associated varicocele between april 2010 and january 2012. |
| PubMedID- 23594355 | This study focuses on the evaluation of these markers in infertile men with varicocele or exposed to occupational background. |
| PubMedID- 22175528 | Forty-five infertile men associated with varicocele and 15 fertile men were subjected to history taking, genital examination and semen analysis. |
| PubMedID- 26097523 | Accumulation of toxic agents including the products of cigarette smoke such as cadmium was reported to be elevated in seminal plasma from infertile men with varicocele (compared with those without varicocele) [99]. |
| PubMedID- 25704993 | Objective: to assess ropporin gene expression in the sperm of infertile asthenozoospermic men with varicocele (vx) before and after repair. |
| PubMedID- 25705240 | Many scholars have recommended that surgery can improve the chances of infertile patients with varicocele fertility in different views. |
| PubMedID- 25999357 | Among infertile men, a diagnosis of unilateral varicocele is made in 90% of varicocele cases and bilateral in the remaining varicocele cases. |
| PubMedID- 26019968 | Patients and methods: in a prospective case-series study, 82 infertile men with varicocele (35 left and 47 bilateral) were evaluated. |
| PubMedID- 25623687 | Results: we identified 445 infertile men with varicocele and abnormal semen parameters by who 1992 or 1999 standards. |
| PubMedID- 26568883 | Routine evaluation of infertile men with varicocele should include a medical and reproductive history, physical examination (incl. |
| PubMedID- 25926610 | However, up to 50% of infertile men without clinical varicocele may have subclinical varicocele, suggesting that subclinical varicocele contributes to infertility.106 in addition, men with unilateral clinical varicocele may also have a subclinical contralateral varicocele 25% of the time.107 several studies, including rcts, have observed improvement in semen parameters without an impact on pregnancy rates in men with subclinical varicocele106108109110111112 (table 2). |
| PubMedID- 26090928 | infertile males with varicocele have the highest percentage of sperm cells with damaged dna, compared to other infertile groups. |
| PubMedID- 24980614 | Serum and seminal plasma leptin, gonadal hormones and semen parameters were evaluated in 10 healthy donors and 42 infertile patients with varicocele before and after surgery. |
| PubMedID- 23658861 | Caşurlu et al40 examined 100 infertile patients without clinical varicocele, 100 infertile patients with clinical varicocele, and 50 fertile men without clinical varicocele, and concluded that venous diameters should not be used as diagnostic criteria for subclinical varicocele because the highest mean diameters of the veins did not differ significantly across the groups. |
| PubMedID- 24472021 | This study aimed to assess glutathione-s-transferase (gst) enzyme- oxidative stress (os) relationship in the internal spermatic vein (isv) of infertile men associated with varicocele (vx). |
| PubMedID- 25652627 | Tawadrous et al.15 found infertile men with varicocele have a relatively low level of seminal plasma antioxidants and high level of lipid peroxidation. |
| PubMedID- 26151891 | Methods: we conducted a prospective and controlled study to evaluate the therapeutic efficacy of mrv and msv for treatment of varicocele in infertile men. |
| PubMedID- 25817105 | Objective: to evaluate the seminal, hormonal, and spontaneous pregnancy outcome after percutaneous embolization of the internal spermatic vein in infertile men with left-sided subclinical varicocele and one or more abnormal semen parameters. |
| PubMedID- 23421634 | To detect 4977-bp deletion in spermatozoa mtdna, semen samples of 60 infertile patients with clinical varicocele and 90 normal men from northern iran were prepared. |
| PubMedID- 23964789 | To evaluate the antioxidant capacity of seminal plasma of infertile men with varicocele before and after an oral supplementation with coenzyme q10 , 38 patients were recruited from a pilot clinical trial. |
| PubMedID- 22984576 | It has also been reported that testicular no production is involved in compromised spermatogenesis in infertile men with varicocele [27]. |
| PubMedID- 21716891 | [1516] indeed, investigators showed that 45% of infertile men with a varicocele had an abnormal acrosome reaction, which could be normalized for many of these men after varicocelectomy. |
| PubMedID- 26278823 | Conclusion: our study demonstrated that both mv and ivdu-mv are effective methods for the improvement of semen parameters in infertile men with varicocele, with a natural conception rate of 35% over a mean follow-up of 21 months. |
| PubMedID- 24578993 | Glutathione supplementation in infertile men with unilateral varicocele or inflammation of the urogenital system leads to a significant improvement in sperm parameters [51]. |
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