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PedAM

Pediatric Disease Annotations & Medicines




Disease vaccinia
Phenotype C0037354|smallpox
Sentences 10
PubMedID- 25919588 Found that smallpox vaccination (vaccinia virus infection) in humans did not significantly alter levels of pre-existing igg to unrelated antigens, including tetanus and measles [29], suggesting that the accelerated declines in vaccine-specific igg observed in association with acute malaria in this study may be specific to plasmodium rather than a general feature of infection.
PubMedID- 21209900 Of the seven known orthopox species, variola virus causes the most severe disease (smallpox) and various forms of the attenuated vaccinia virus are used for vaccination.
PubMedID- 21933385 For example, in 2009 vigiv was used to treat a military smallpox vaccinee with progressive vaccinia [48].
PubMedID- 22258709 Successful vaccination against smallpox with conventional vaccinia virus is usually determined by the development of a vesicular skin lesion at the site of vaccinia inoculation, called a "take." although previous vaccination is known to be associated with attenuation of the take, the immunology that underlies a no-take in vaccinia-naive individuals is not well understood.
PubMedID- 21829313 Vaccination against smallpox is performed with the vaccinia virus, which has many antigenic structures in common with the smallpox agent.
PubMedID- 23571177 Unintentional transfer of vaccinia virus associated with smallpox vaccines: acam2000((r)) compared with dryvax((r)).
PubMedID- 20566929 Conclusions: we present the first confirmed case of generalized vaccinia following immunization with the second-generation smallpox vaccine acam2000.
PubMedID- 23133652 The smallpox vaccine consists of live vaccinia virus (vacv) and, from a public health perspective, is the gold standard of vaccines because it has led to the complete eradication of wild smallpox (variola virus) from the human population [4].
PubMedID- 26239454 Ev is a rare, potentially life-threatening eruption that develops in predisposed individuals either after immunization for smallpox with live, attenuated vaccinia virus or physical contact with a recently vaccinated individual [48].
PubMedID- 21499452 Results of the eind experience have been reported for the use of cmx001 to treat recurrent cmv (a case series involving three transplant patients who had failed valganciclovir therapy), adv infection (a case series of thirteen immunocompromised patients with a median age of 12 years, range 0.75 to 66, with disseminated adv infection) and progressive vaccinia (a single case with complications from smallpox vaccination).

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