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PedAM

Pediatric Disease Annotations & Medicines




Disease uveitis
Phenotype C0271051|macular edema
Sentences 12
PubMedID- 24024057 Four female patients affected by jia-related chronic anterior uveitis (cau),complicated by severe macular edema, were retrospectively analyzed.
PubMedID- 23807831 macular edema is one of the manifestations of uveitis leading to loss of central vision and reduced visual acuity.
PubMedID- 24696869 They offer an alternative route in the management of macular edema due to uveitis, retinal vein occlusion, diabetes and pseudophakia.
PubMedID- 20714178 More recently, increased clinical use of locally delivered gc has shown significant benefit for the treatment of multiple retinal indications including macular edema associated with uveitis, retinal vascular occlusions and diabetes.
PubMedID- 23786783 Interferon versus methotrexate in intermediate uveitis with macular edema: results of a randomized controlled clinical trial.
PubMedID- 22783878 Sustained-release intraocular implants have been approved for posterior uveitis and rvo associated with macular edema.
PubMedID- 25135585 If the third measurement is reliable, the difference of the value from the first or second measurement is up to 3 db, and visual field abnormality is recognized in the two measurementsocular exclusion criteria (applies to the eye evaluated) 1. under treatment for glaucoma or ocular hypertension 2. either eye enucleated or eviscerated 3. cone-rod dystrophy with primarily impaired cone function 4. history of other ocular disease that can confound the outcome of the study (e.g., diabetic retinopathy, uveitis) 5. complicated by remarkable cystoid macular edema, epimacular membrane, or macular traction syndrome, diagnosed by oct 6. complicated by a nuclear cataract of moderate grade (grade 3, emery classification), an anterior subcapsular cataract, or a posterior subcapsular cataract, that may seriously affect vision 7.
PubMedID- 25134495 Tofacitinib is fda approved for rheumatoid arthritis and sotrastaurin currently studied in phase 2 trials in patients with macular edema associated with uveitis offer examples of this approach, respectively.
PubMedID- 22661129 Prior studies have shown that srds are found in 15–20 % of uveitis patients with macular edema [3, 5], but there is conflicting literature as to the correlation between the presence of srd and decreased visual acuity.
PubMedID- 23514443 Ozurdex® (allergan, inc.) has already obtained fda approval for intravitreal use for macular edema due to non-infectious uveitis or retinal vein occlusions [5].
PubMedID- 24347829 In one retrospective study, tocilizumab was found to be efficacious in treating uveitis patients with cystoid macular edema that was refractory to intraocular steroids or other immunosuppressive therapies [25].
PubMedID- 20337324 The case of a 44-year-old woman who was under treatment for bilateral recurrent anterior uveitis with chronic cystoid macular edema for two and a half years.

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