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PedAM

Pediatric Disease Annotations & Medicines




Disease uveal melanoma
Phenotype C0025202|melanoma
Sentences 5
PubMedID- 25874144 In the collaborative ocular melanoma study (coms) of primary uveal melanoma only 3 (<1%) of 739 patients with uveal melanoma had metastasis to the contralateral eye or orbit [19].
PubMedID- 23825798 However, to our knowledge, this is one of the largest studies to date looking specifically at germ-line mutations in familial melanoma pedigrees with uveal melanoma and/or blue nevi.
PubMedID- 23772126 Ciliary body melanoma represents 6–15% of uveal melanoma.
PubMedID- 24653816 This concept is supported by recent studies that have shown circulating melanoma cells in patients with uveal melanoma independent of tumor size, type of treatment, or length of follow-up.10 therefore, circulating melanoma cells are thought to colonize in distant organs, form micrometastases, and remain dormant while sporadically seeding tumor cells into the circulating blood.
PubMedID- 25904122 The prevalence of cutaneous melanoma was increased in patients with uveal melanoma, but the lifetime prevalence of other primary cancers was not appreciably increased.

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