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PedAM

Pediatric Disease Annotations & Medicines




Disease urolithiasis
Phenotype C0948265|metabolic syndrome
Sentences 5
PubMedID- 25873954 Several hypotheses have been proposed to explain the pathophysiology of urolithiasis resulting from metabolic syndrome, amongst which are the insulin resistance and randall's plaque hypothesis.
PubMedID- 22666789 However, the metabolic syndrome in patients with urolithiasis seems to be more common in aging individuals than in younger individuals (30).
PubMedID- 24518782 The susceptibility to urolithiasis of patients with metabolic syndrome might be due to aggravated inflammation of renal tubular cells triggered by a paracrine mechanism involving these 3 cell types.
PubMedID- 23180816 White skin colour, family history, and metabolic syndrome were independently associated with urolithiasis (p < 0.05).
PubMedID- 23326218 Conducted a study in 2008 and showed a two-fold increase in urolithiasis prevalence in patients with metabolic syndrome [9].

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