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PedAM

Pediatric Disease Annotations & Medicines




Disease ureteral obstruction
Phenotype C0151650|renal fibrosis
Sentences 16
PubMedID- 24550650 Tempol attenuates renal fibrosis in mice with unilateral ureteral obstruction: the role of pi3k-akt-foxo3a signaling.
PubMedID- 25120589 Protective effects of quercetin and hyperoside on renal fibrosis in rats with unilateral ureteral obstruction.
PubMedID- 26174456 This study aimed to investigate the effect of klotho protein on er stress-related apoptosis and renal fibrosis in rates with unilateral ureteral obstruction (uuo).
PubMedID- 24083846 The effect of simvastatin and erythropoietin on renal fibrosis in rats with unilateral ureteral obstruction.
PubMedID- 25630829 Purpose: to assess the apparent diffusion coefficient (adc) derived from diffusion-weighted (dw) magnetic resonance imaging (mri) as a specific marker of renal fibrosis in rats with unilateral ureteral obstruction (uuo).
PubMedID- 26227493 Knockdown of rtn1a expression in vivo attenuates er stress and renal fibrosis in mice with unilateral ureteral obstruction, and also attenuates er stress, proteinuria, glomerular hypertrophy and mesangial expansion in diabetic mice.
PubMedID- 25620133 Ks370g, a caffeamide derivative, attenuates unilateral ureteral obstruction-induced renal fibrosis by the reduction of inflammation and oxidative stress in mice.
PubMedID- 24393202 Oleanolic acid attenuates renal fibrosis in mice with unilateral ureteral obstruction via facilitating nuclear translocation of nrf2.
PubMedID- 24489579 Demonstrated that cd4+ depletion caused a reduction in renal fibrosis due to ureteral obstruction [21].
PubMedID- 25130652 Unilateral ureteral obstruction (uuo)-induced renal fibrosis was associated with an increase in fgf2 and a reduction in klotho expression in wild-type mice, whereas fgf2(-/-) mice largely preserved klotho expression and developed only mild renal fibrosis after obstructive injury.
PubMedID- 20470302 Aim: to examine the additive protective effects of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone (pio) and the angiotensin ii receptor blocker candesartan (cand) in a murine model of renal fibrosis: mice with unilateral ureteral obstruction (uuo).
PubMedID- 20195239 We first found a progressive increase in epimorphin expression corresponding to the progression of renal fibrosis in mice with unilateral ureteral obstruction (uuo).
PubMedID- 26221756 The smad3/smad4/cdk9 complex promotes renal fibrosis in mice with unilateral ureteral obstruction.
PubMedID- 23264954 ureteral obstruction-induced renal fibrosis: an in vivo platform for mechanistic discovery and therapeutic intervention.
PubMedID- 22143161 In this study, we investigated the role of reactive oxygen species and testosterone in the progression of renal fibrosis in mice with unilateral ureteral obstruction (uuo).
PubMedID- 24333535 Protective role of jak/stat signaling against renal fibrosis in mice with unilateral ureteral obstruction.

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