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PedAM

Pediatric Disease Annotations & Medicines




Disease ulcerative colitis
Phenotype C0007102|colon cancer
Sentences 11
PubMedID- 23202913 It has been shown that dna methylation is more frequent and more common in non-neoplastic cells in the mucosa from ulcerative colitis patients with colon cancer as opposed to those with non-neoplastic mucosa from ulcerative colitis without cancer.
PubMedID- 25443414 The present study explores the role of ulcerative colitis in colon cancer by investigating the activities of tyrosine kinase activated mapk pathway and various components of the pi3k pathway including pi3k, pten, pdk1, gsk3beta, akt, mtor, wnt and beta-catenin.
PubMedID- 26189522 Here we report a case of advanced gastric cancer seen after total proctocolectomy for an early colon cancer associated with ulcerative colitis (uc).
PubMedID- 23546389 Dna hypermethylation of a selective gene panel as a risk marker for colon cancer in patients with ulcerative colitis.
PubMedID- 20085438 Objectives: to determine the incidences of dysplasia, adenomatous polyp and colon cancer in patients with ulcerative colitis (uc) and to evaluate the risk factors.
PubMedID- 26296091 For example, inflammatory bowel diseases, such as ulcerative colitis, are associated with colon cancer [26].
PubMedID- 26369263 A case of colon cancer associated with ulcerative colitis: evaluation using ct colonography.
PubMedID- 24210073 These preclinical studies suggest that fty720/fingolimod may be useful in treating colon cancer in individuals with ulcerative colitis.
PubMedID- 23095257 Although rna-sequencing data in patients affected by ibd would provide more consistency to the description of this process, the analysis performed shows a higher correlation of ulcerative colitis genomic patterns with colon cancer in comparison to crohn's disease.
PubMedID- 23273921 The prodrug fty720 decreased sphk1 and s1pr1 expression and eliminated the nf-kappab/il-6/stat3 amplification cascade and development of cac, even in sphk2(-/-) mice, and may be useful in treating colon cancer in individuals with ulcerative colitis.
PubMedID- 22848611 A novel murine model of inflammatory bowel disease and inflammation-associated colon cancer with ulcerative colitis-like features.

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