PedAM
Pediatric Disease Annotations & Medicines
| Disease | tuberculosis |
| Phenotype | C0151332|active tuberculosis |
| Sentences | 11 |
| PubMedID- 26483793 | Mait cells may be particularly involved in the immune response against mycobacterium tuberculosis: patients with active tuberculosis show a depleted blood mait cell compartment resulting from their recruitment to the lung (33, 38–40). |
| PubMedID- 26339658 | In addition, we have recently observed significantly enhanced ifn-γ responses to specific antigens of m. tuberculosis in patients with active tuberculosis [55]. |
| PubMedID- 23966657 | A smaller percentage of ppd- and rd1-peptide-specific cd4+ cells expressed cd127 in active tuberculosis compared with latent tuberculosis infection, for example, a lower percentage of ppd-specific cd4+ ifn-γ-only- and tnf-α-only-secreting cells expressed cd127 in active tuberculosis compared with latent tuberculosis infection (p < .001 and p = .003, respectively; figure 3b). |
| PubMedID- 25426782 | Ifng-mediated immune responses enhance autophagy against mycobacterium tuberculosis antigens in patients with active tuberculosis. |
| PubMedID- 22227512 | The prevalence of endobronchial tuberculosis (ebtb) in patients with active tuberculosis is about 10% to 40%. |
| PubMedID- 23278987 | The importance of chemoprophylaxis should be emphasized to minimize the risk of developing active tuberculosis in patients with latent tuberculosis infection undergoing solid organ transplantation. |
| PubMedID- 26409285 | Igg directed against specific mtb antigens, present in individuals with latent tuberculosis but not in patients with active tuberculosis, could be tailored for intravenous administration, following in vitro confirmation of antituberculosis activity. |
| PubMedID- 24665150 | Introduction: interferon-gamma (ifn-gamma) is essential for defence against mycobacterium tuberculosis; however, levels in patients with active tuberculosis (tb) and changes during treatment have not been documented in our tuberculosis patients in nigeria, hence this study has been carried out. |
| PubMedID- 26319069 | Mycobacterium tuberculosis (m.tb) infection leads to active tuberculosis (tb), a disease that kills one human every 18s. |
| PubMedID- 24977684 | Summary: more sensitive diagnostics in deceased donors are needed to quantify the risk of tb transmission and the risk of progression to active tuberculosis in those with latent tuberculosis infection prior to transplant. |
| PubMedID- 26493989 | We derived a hypothesis that household contacts of active tuberculosis patients with latent tuberculosis infection would present with mixed th1/th2 cytokine profiles, dominated by high concentrations of th1 cytokines (due to recent exposure), but accompanied by th2 and regulatory cytokine production as a result of the on-going immune modulating effects of m.tb infection. |
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