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PedAM

Pediatric Disease Annotations & Medicines




Disease toxic megacolon
Phenotype C0009319|colitis
Sentences 13
PubMedID- 26019473 Severe ulcerative colitis complicated by toxic megacolon and gravidic sepsis was diagnosed by clinical evaluation, colonoscopy, and rectal biopsy that were performed safely without risk for the mother or baby.
PubMedID- 22863963 [a case of pseudomembranous colitis concomitant with toxic megacolon and paralytic ileus].
PubMedID- 24592552 We report two cases of steroid and antibiotic-refractory fulminant crohn's colitis, complicated by toxic megacolon, who were successfully treated with infliximab (ifx), thus avoiding surgical intervention.
PubMedID- 23158919 [toxic megacolon complicated by ulcerative colitis in six patients: a case report and literature review].
PubMedID- 23113897 The clinical picture varies from self-limiting diarrhea to pseudomembranous colitis with toxic megacolon and ultimately death.
PubMedID- 24729736 In adolescents with uc the indications for colectomy include: asc unresponsive to medical therapy, severe colitis complicated by toxic megacolon and/or perforation, intractable chronic colitis unresponsive to medical therapies and also following the finding of precancerous changes.
PubMedID- 25518056 Younger age at diagnosis and surgery, family history of ibd, toxic megacolon/fulminant colitis, pre-diversion severe diarrhea, prediversion anti-tnf biological therapy, arthralgia/arthropathy and staged surgery were more common in the si group (p < 0.05).
PubMedID- 22009735 Less frequently, toxic megacolon has been attributed to ischemic colitis, collagenous colitis, or obstructive colorectal cancer.
PubMedID- 21857531 We report a case of a woman with steroid and antibiotic-refractory fulminant crohn colitis and ileitis, complicated by a toxic megacolon, who was successfully treated with infliximab.
PubMedID- 24858336 Fecal transplant for treatment of toxic megacolon associated with clostridium difficile colitis in a patient with duchenne muscular dystrophy.
PubMedID- 25673592 There was extensive pseudomembranous colitis and appendicitis with changes of toxic megacolon.
PubMedID- 20805934 The clinical picture of a c. difficile infection varies from an asymptomatic carrier to fulminant colitis with toxic megacolon.
PubMedID- 23037465 We herein present the case of a 57-year-old man with toxic megacolon associated with cmv colitis in corticosteroid-naive ulcerative colitis (uc).

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