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PedAM

Pediatric Disease Annotations & Medicines




Disease tic disorder
Phenotype C0035078|renal failure
Sentences 4
PubMedID- 20534299 This genetic disorder, which frequently leads to end-stage renal failure, often recurs in kidney transplants, resulting in the poorest graft outcomes among all atypical hus forms, due to a mutation in genes encoding complement components and regulatory proteins.
PubMedID- 24998259 Background: autosomal dominant polycystic kidney disease (adpkd) is the most common genetic disorder leading to end-stage renal failure in humans.
PubMedID- 25165573 Autosomal dominant polycystic kidney disease (adpkd) is the most common genetic disorder leading to end-stage renal failure.
PubMedID- 22399868 Several recent reports have demonstrated that early use of biologics can ameliorate polyarthralgia and skin lesions in rheumatic disorders, including psa, associated with chronic renal failure on hemodialysis (table 1).5–12 biologics targeting tnf are most frequently used in this situation, and among them etanercept has been reported to show pharmacokinetics similar to those in healthy subjects even under chronic renal failure on hemodialysis.13 however, the use of etanercept is not allowed in psa in japan.

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