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PedAM

Pediatric Disease Annotations & Medicines




Disease tic disorder
Phenotype C0030312|bone marrow failure
Sentences 4
PubMedID- 23209944 Fanconi anemia is an inherited genetic disorder leading to bone marrow failure and high incidence of leukemia [114].
PubMedID- 24799500 Fanconi anemia is a rare genetic disorder that can lead to bone marrow failure, congenital abnormalities, and increased risk for leukemia and cancer.
PubMedID- 23926327 In this study, we report that deregulation of notch signaling skews hsc differentiation in mouse models of fanconi anemia (fa), a genetic disorder associated with bone marrow failure and progression to leukemia and other cancers.
PubMedID- 25002988 Fanconi anemia (fa) is a rare autosomal recessive genetic disorder associated with a bone marrow failure, cancer predisposition and hypersensitivity to dna crosslinking agents.

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