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PedAM

Pediatric Disease Annotations & Medicines




Disease tic disorder
Phenotype C0002871|anemia
Sentences 4
PubMedID- 23555700 We hypothesized that changes in either systemic or intestinal copper status regulate hif-2α and as consequence iron absorption genes since: (i) we and others have shown that cybrd1, slc11a2 and slc40a1 are bona fide hif-2α targets [6], [7]; (ii) in vitro evidence suggests that changes in cellular copper levels regulate hif-1α [20] and (iii) anemia associated with genetic disorders of copper metabolism could lead to increases in tissue hypoxia and stabilize hif-2α [21]–[25].
PubMedID- 23085440 Background and aims: in brazil, sickle cell anemia (sca) is one of the most common genetic disorders.
PubMedID- 21811372 anemia due to hemopoitic disorder (post-chemotherapy or rt) needs proper evaluation and appropriate management with growth factors or fractionated red blood cells.
PubMedID- 24853873 However, this genetic disorder may be associated with potential hemolytic anemia after treatment with anti-malarials, primaquine or other 8-aminoquinolines.

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