Disease | thrombocytosis |
Phenotype | C0027022|myeloproliferative neoplasms |
Sentences | 4 |
PubMedID- 22381681 | This study provides new insights into the mechanisms underlying lbh589-induced thrombocytopenia and provides a rationale for using tubulin as a target for selective histone deacetylase inhibitor therapies to treat thrombocytosis in patients with myeloproliferative neoplasms. |
PubMedID- 22084665 | The “classic” myeloproliferative neoplasms (mpns), comprised of essential thrombocythemia (et), chronic myeloid leukemia (cml), polycythemia vera (pv), and primary myelofibrosis (pmf) [41] are the most common clonal processes associated with thrombocytosis. |
PubMedID- 24114627 | Classical myeloproliferative neoplasms (mpns) are composed of essential thrombocythemia (et), polycythemia vera (pv) and myelofibrosis (mf), the etiology of which is largely unknown. |
PubMedID- 22170483 | The bcr/abl-negative myeloproliferative neoplasms (mpns) of essential thrombocythemia, polycythemia vera, and primary myelofibrosis, over the natural course of their disease, have an increasing predisposition to transform to overt acute myeloid leukemia (aml)-most appropriately referred to as mpn-blast phase (mpn-bp). |
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