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PedAM

Pediatric Disease Annotations & Medicines




Disease thrombocytosis
Phenotype C0027022|myeloproliferative disorders
Sentences 4
PubMedID- 20586925 Background: anagrelide is a selective inhibitor of megakaryocytopoiesis used to treat thrombocytosis in patients with chronic myeloproliferative disorders.
PubMedID- 24744668 In patients with thrombocythemia associated with chronic myeloproliferative disorders, increased hematocrit and viscosity aggravate the platelet-mediated microvascular ischemic and thrombotic syndrome of thrombocythemia to major arterial and venous thrombotic complications.
PubMedID- 25807961 Controversies still exist regarding definition of the thrombotic risks in ph- (bcr/abl1-) myeloproliferative disorders with thrombocythemia (mpd-t).
PubMedID- 21312258 myeloproliferative disorders may present with thrombocytosis and/or leukocytosis with symptoms ranging from minor to life-threatening.

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