PedAM
Pediatric Disease Annotations & Medicines
| Disease | thrombocytopenia |
| Phenotype | C1260402|splenic sequestration |
| Sentences | 3 |
| PubMedID- 22259634 | Although plts were slightly reduced (87×109/l), thrombocytopenia might result from splenic sequestration and severe bm suppression rather than dic. |
| PubMedID- 22563238 | However, pathological lipid accumulation in macrophages accounts for less than 2% of the additional tissue mass in the liver and spleen; the additional increase is attributed to an inflammatory and infiltrative cellular response.23 thrombocytopenia and anemia result from splenic sequestration, with a contribution from marrow failure, as shown by the long-term evolution of the disease after splenectomy. |
| PubMedID- 23091811 | The possible causes of thrombocytopenia include splenic sequestration of platelets, suppression of platelet production in the bone marrow and decreased activity of the hematopoietic growth factor, thrombopoietin. |
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