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PedAM

Pediatric Disease Annotations & Medicines




Disease thrombocytopenia
Phenotype C0155765|microangiopathy
Sentences 8
PubMedID- 23442444 Thrombotic microangiopathy is another cause of sunitinib-mediated thrombocytopenia, reported by kapiteijn et al.
PubMedID- 22507807 Except in the occasional situations in which thrombocytopenia is associated with thrombotic microangiopathy, such as catastrophic aps, bleeding is uncommon in aps patients.
PubMedID- 25852897 thrombocytopenia with or without microangiopathy following quinine is often referred to as quinine ‘hypersensitivity’.
PubMedID- 23607458 Typical haemolytic uraemic syndrome (hus) is caused by shiga toxin (stx)-producing escherichia coli infections and is characterized by thrombotic microangiopathy that leads to haemolytic anaemia, thrombocytopenia and acute renal failure.
PubMedID- 22851928 Typical hus is a thrombotic microangiopathy with hemolytic anemia, thrombocytopenia and acute renal failure that is epidemic, diarrhea related and caused by verotoxin (shiga toxin)-producing escherichia coli (o157:h7, o104:h4).
PubMedID- 23300888 Fifteen patients (11%) developed thrombotic microangiopathy with thrombocytopenia and fragmented red blood cells in all 15 cases, acute renal failure with anuria/oliguria in ten cases and an abnormal creatinine without renal failure in five.
PubMedID- 20350374 Hus is a thrombotic microangiopathy and consists of nonimmune hemolytic anemia, thrombocytopenia, and renal failure (1).
PubMedID- 22309967 In adults, the difficulty of differentiating ttp, which is much more common than hus and the need for a speedy diagnosis to provide life-saving plasma therapy has resulted in the term ttp/hus for adult forms of thrombotic microangiopathy that present with unexplained thrombocytopenia and microangiopathic hemolytic anemia without a dic.

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