PedAM
Pediatric Disease Annotations & Medicines
| Disease | thrombocytopenia |
| Phenotype | C0024530|malaria |
| Sentences | 18 |
| PubMedID- 21073022 | Platelet transfusions are not required for malaria patients with thrombocytopenia who have no bleeding. |
| PubMedID- 23723981 | High frequency of thrombocytopenia in patients with malaria has been well-documented in several studies [8], including reports from manaus in the brazilian amazon [8], [9]. |
| PubMedID- 25285308 | Nevertheless, thrombocytopenia in malaria is observed to improve with disease resolution, and a normal platelet count is usually reported within 7 days after the initiation of antimalarial treatment [21, 39]. |
| PubMedID- 23888081 | This is not surprising because thrombocytopenia is associated with cerebral malaria [11, 12], and in fact children in this study had lower levels of platelets. |
| PubMedID- 24490093 | Unusual presentation of vivax malaria with anaemia, thrombocytopenia, jaundice, renal disturbance, and melena: a report from malang, a nonendemic area in indonesia. |
| PubMedID- 24324686 | thrombocytopenia in malaria is reported to be a consequence of anti-body induced platelet destruction, coagulopathy and platelet adhesion to the activated endothelium [47, 48]. |
| PubMedID- 24327084 | Conclusions: vivax malaria is associated with transient thrombocytopenia which does not lead to significant bleeding in children. |
| PubMedID- 23777034 | Resurgence of complicated malaria associated with severe thrombocytopenia in a tertiary care hospital in delhi. |
| PubMedID- 22866922 | P. falciparum malaria is associated with thrombocytopenia in pregnant women in eastern sudan. |
| PubMedID- 23350022 | The pathogenesis of thrombocytopenia in malaria have been suggested due to peripheral destruction, splenic pooling or consumption coagulopathy but de mast et al have hypothesized that thrombocytopenia in early malaria is associated with gpib shedding in absence of systemic platelet activation and consumptive coagulopathy.25 malaria is considered to show seasonal variation in india with maximum prevalence in rainy season from july to november.7 the study also showed that positive predictive value of thrombocytopenia for the malaria infection increased during the months of july to october when maximum number of cases were reported in the laboratory while it decreased during the other months and thus the role of thrombocytopenia as predictor for malaria is retained and shows increase when the incidence of malaria increases. |
| PubMedID- 22811952 | Fifty-three percent of patients with malaria showing thrombocytopenia in our study is close to others reporting low platelets as 57% [9] and 48% [10]. |
| PubMedID- 25604366 | thrombocytopenia in malaria: can platelet counts differentiate malaria from other infections. |
| PubMedID- 21687657 | These features are not consistent with thrombocytopenia in malaria, especially in acute uncomplicated knowlesi malaria where thrombocytopenia is a characteristic. |
| PubMedID- 23155405 | Since platelets are a major reservoir of rantes in the circulation [41], it has been suggested that lower levels of rantes in patients with severe malaria may be due to parasite-induced thrombocytopenia [42]. |
| PubMedID- 25928218 | thrombocytopenia is commonly associated with malaria in hiv- populations [35, 36] and our data is consistent with a recent study that also reported normal platelet counts in hiv co-infected subjects [37]. |
| PubMedID- 22289302 | A study investigating the relationship that parasite density has on platelet count showed that malaria-infected children with thrombocytopenia (decreased platelet count) were younger, had higher parasitaemia, lower hemoglobin levels, an increased mean platelet volume, and exhibited platelet aggregation [72]. |
| PubMedID- 24572501 | The mechanisms that produce thrombocytopenia in malaria are not known but seem related to a greater severity of illness (25). |
| PubMedID- 19626579 | malaria may be complicated by development of thrombocytopenia, elevated liver enzymes, and/or hemolysis, which may be difficult to distinguish from hellp (hemolytic anemia; elevated liver enzymes; low platelet count) syndrome in a pregnant patient. |
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