PedAM
Pediatric Disease Annotations & Medicines
| Disease | thrombocytopenia |
| Phenotype | C0023895|liver disease |
| Sentences | 22 |
| PubMedID- 21161560 | Chronic liver disease increases the risk of linezolid-related thrombocytopenia in methicillin-resistant staphylococcus aureus-infected patients after digestive surgery. |
| PubMedID- 23086124 | thrombocytopenia in patients with chronic liver disease: what's in a name. |
| PubMedID- 23339384 | Correcting thrombocytopenia in patients with liver diseases: a difficult hurdle. |
| PubMedID- 26413522 | Since previous studies indicate that thrombocytopenia results from chronic liver disease, we speculated that a haematological comparison between a healthy blood donor and a donor with hcv might reveal the impact of hcv on plt and tpo; an improved understanding of this impact could help determine whether a donor has hcv. |
| PubMedID- 21637276 | Small intestinal bacterial overgrowth and helicobacter pylori: can they be cause of thrombocytopenia in patients with chronic liver disease. |
| PubMedID- 22674141 | We evaluated the pharmacokinetics, efficacy, and safety of eltrombopag in japanese patients with thrombocytopenia associated with chronic liver disease (cld). |
| PubMedID- 22414142 | Estimates of the prevalence of thrombocytopenia in liver disease vary widely, depending on the population and the platelet threshold used [5,6]. |
| PubMedID- 24714308 | No correlation between the size of the spleen and the amount of platelet specific immunoglobulin was found, and this may partly explain the inconstant relationship between the size of the spleen and the degree of thrombocytopenia in patients with chronic liver disease [9]. |
| PubMedID- 24100055 | Background: thrombocytopenia in patients with end-stage liver disease is a common disorder caused mainly by portal hypertension, low levels of thrombopoetin, and endotoxemia. |
| PubMedID- 21131941 | thrombocytopenia associated with chronic liver disease: effects of rifaximin on platelet count. |
| PubMedID- 26191473 | We regarded a patient to have liver injury based on the following clinical data: (1) elevation of serum aspartate aminotransferase (ast) and/or alanine aminotransferase (alt) levels, or (2) the existence of primary liver disease associated with thrombocytopenia with platelet counts below 100,000/μl. |
| PubMedID- 20565378 | Despite prolonged coagulation times and thrombocytopenia associated with end-stage liver disease, formation of thrombi in the circulation seems to occur more frequently during liver transplant than during any other type of major surgery. |
| PubMedID- 24686514 | These agents are currently in development for the treatment of thrombocytopenia in patients with chronic liver disease and liver cirrhosis [80–82]. |
| PubMedID- 26501978 | Currently, two global phase iii trials are ongoing evaluating the efficacy and safety of once-daily oral avatrombopag for the treatment of adults with thrombocytopenia associated with liver disease prior to an elective procedure (clinical trial no: nct01972529 and nct01976104). |
| PubMedID- 26459859 | Overall the current study gives a better understanding of a novel approach to deal with thrombocytopenia associated with liver diseases with elevated ucb. |
| PubMedID- 22257364 | Eltrombopag is not yet licensed for treatment of thrombocytopenia in patients with chronic liver disease because the risk of portal venous thrombosis (pvt) increased substantially when this drug was administered at 75 mg daily for 14 days [33]. |
| PubMedID- 24696622 | Similarly, chronic liver disease patients with thrombocytopenia who need to undergo an invasive procedure may be potential candidates for short two-week courses of eltrombopag in the periprocedural period to help reduce the risk of bleeding. |
| PubMedID- 20919743 | Given the fact that thrombocytopenia is associated with chronic liver diseases, and the multifunctional nature of platelets we reason that phenotype-specific platelets could be the systemic barometer for hepato-carcinogenesis. |
| PubMedID- 26573200 | [a case report of immune thrombocytopenia with drug induced liver disease]. |
| PubMedID- 24375285 | Co-existing liver disease increases the risk of postoperative thrombocytopenia in patients undergoing hepatic resection: implications for the risk of epidural hematoma associated with the removal of an epidural catheter. |
| PubMedID- 22054278 | Romiplostim in chronic liver disease with severe thrombocytopenia undergoing an elective invasive procedure. |
| PubMedID- 24478597 | It is stillcontroversial whether the thrombocytopenia observed in patients with chronic liver diseaseis more associated to splenomegaly or to very high portal blood pressure. |
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