PedAM
Pediatric Disease Annotations & Medicines
| Disease | thalassemia |
| Phenotype | C0019045|haemoglobinopathies |
| Sentences | 2 |
| PubMedID- 23807756 | Background: haemoglobinopathies, inherited disorders of haemoglobin synthesis (thalassaemia) or structure (sickle cell disease), are responsible for significant morbidity and mortality throughout the world. |
| PubMedID- 23115690 | The thalassemias share with the sickle haemoglobinopathies characteristics such as accelerated hemoglobin denaturation and degradation, excess free iron release, heightened oxidative stress, a hypercoagulable state, and widespread vascular damage. |
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