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PedAM

Pediatric Disease Annotations & Medicines




Disease thalassemia
Phenotype C0002895|sickle cell anemia
Sentences 5
PubMedID- 22065975 The interaction of α-thalassemia with sickle cell anemia (hemoglobin ss disease, hbss) is known to influence hematological indices, reduce hemolytic rate and intravascular sickling, and increase deformation of the red blood cells.
PubMedID- 25869286 The thalassemias, together with sickle cell anemia and its variants, are the world's most common form of inherited anemia, and in economically undeveloped countries, they still account for tens of thousands of premature deaths every year.
PubMedID- 20712767 The thalassemias, together with sickle cell anemia and its variants, are by far the most common monogenic diseases.
PubMedID- 24324305 However, when group i (beta thalassemia) was compared with group ii (sickle cell anemia), results were found to highly significant (p<0.001) only for decayed missing filled tooth.
PubMedID- 24399969 Found significantly increased plasma concentrations of anti-spectrin nabs in splenectomized patients with β-thalassemia major and in patients with sickle cell anemia (wiener et al., 1986).

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