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PedAM

Pediatric Disease Annotations & Medicines




Disease temporal lobe epilepsy
Phenotype C0039614|tetanus
Sentences 3
PubMedID- 23439313 The central results from this study are that the spontaneously-seizing tetanus toxin model of temporal lobe epilepsy in the absence of status epilepticus results in a ~ 5-fold increase in brdu labeled cells in both the injected and contralateral hippocampi during the second week after induction.
PubMedID- 20400525 The tetanus toxin model of temporal lobe epilepsy, as implemented here, is non-lesional: most animals lack hippocampal sclerosis and detectable neuronal loss; a minority, fewer than 10%, of animals do have a focal loss of ca1 pyramidal cells reminiscent of hippocampal sclerosis, extending 1–2 mm (jefferys et al., 1992).
PubMedID- 23184516 A, synchronization between the hippocampus (hippo) and entorhinal cortex (ec) was examined before and during seizure in a tetanus toxin model of temporal lobe epilepsy (jiruska et al.

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