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PedAM

Pediatric Disease Annotations & Medicines




Disease syndrome of inappropriate antidiuretic hormone
Phenotype C0023890|cirrhosis
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PubMedID- 24573394 Tolvaptan is a selective, competitive vasopressin receptor 2 antagonist used to treat hyponatremia associated with congestive heart failure, cirrhosis and the syndrome of inappropriate antidiuretic hormone (siadh).
PubMedID- 20923561 Defects in both urine concentrating and diluting ability have been measured in chronic kidney diseases, and in diseases outside the kidneys associated with either fluid retention as heart failure, liver cirrhosis and syndrome of inappropriate antidiuretic hormone secretion or dehydration as diabetes insipidus [1-3].

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