PedAM
Pediatric Disease Annotations & Medicines
| Disease | splenomegaly |
| Phenotype | C0039730|thalassemia |
| Sentences | 3 |
| PubMedID- 20508726 | The discovery of jak2 as an important mediator of ie and splenomegaly in β-thalassemia suggests that the use of small organic molecules to inhibit jak2 could be beneficial in reducing ie and splenomegaly. |
| PubMedID- 20877478 | During the same period, 12 patients of β thalassemia with grade iv splenomegaly and hepatomegaly were electively subjected to open splenectomy. |
| PubMedID- 22924029 | Episodes of splenic sequestration in adults are generally mild and have been reported in patients with hemoglobin sc disease and sickle β+ thalassemia at risk due to occasional persistent splenomegaly into adulthood [18]. |
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