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PedAM

Pediatric Disease Annotations & Medicines




Disease splenomegaly
Phenotype C0030312|pancytopenia
Sentences 6
PubMedID- 25332634 Hairy cell leukemia (hcl) is characterized by pancytopenia and usually associated with massive splenomegaly, however the same may not be true in the clinical settings.
PubMedID- 24744957 The observed pancytopenia is correlated with splenomegaly, hemolysis, inefficient erythropoiesis, reticuloendothelial hyperplasia with abnormal iron retention by macrophages, and autoimmune hemolytic anemia [5].
PubMedID- 21651767 Three weeks prior she had undergone a splenectomy for pancytopenia associated with splenomegaly caused by hepatitis b cirrhosis-related portal hypertension without esophageal varices (figure 1).
PubMedID- 24782931 Hcl should be included in the differential diagnoses of pancytopenia with or without splenomegaly which is highlighted by this case.
PubMedID- 25956701 Extra-renal cystine accumulation caused multiple endocrinopathies (including adrenal insufficiency, hypothyroidism and primary hypogonadism), neurological symptoms, pancytopenia owing to splenomegaly and portal hypertension due to nodular regenerative hyperplasia, aggravated by splenic vein thrombosis and partial portal vein thrombosis.
PubMedID- 22227513 Progressive splenomegaly with pancytopenia (hypersplenism) is associated with epoprostenol use in poph.

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