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PedAM

Pediatric Disease Annotations & Medicines




Disease splenomegaly
Phenotype C0023418|leukemia
Sentences 4
PubMedID- 26500848 The spleen/body weight ratio was increased by 15-fold in mice engrafted with aml compared to sublethally irradiated but non-engrafted mice, demonstrating splenomegaly associated with leukemia involvement.
PubMedID- 23626802 In the ef1α group, three secondary mice developed t-cell leukemia with enlarged spleen and thymus (table s1).
PubMedID- 26097891 Control mice developed overt disseminated leukemia with massive splenomegaly and an average nucleated spleen cell count of 178 ± 60 × 106 (log10 count: 7.8 ± 0.3) that was significantly higher than the nucleated spleen counts of non-leukemic control ns mice (4.6 ± 0.4 × 106, log10 count: 6.6 ± 0.4, p < 0.0001) (fig.
PubMedID- 24466546 Chronic myeloid leukemia with marked splenomegaly and pseudo-gaucher cells.

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