PedAM
Pediatric Disease Annotations & Medicines
| Disease | splenomegaly |
| Phenotype | C0020541|portal hypertension |
| Sentences | 25 |
| PubMedID- 26284329 | Signs of portal hypertension with ascites, and splenomegaly were present. |
| PubMedID- 22267006 | Traditionally, splenomegaly in portal hypertension is thought to be a mere consequence of the rise of portal venous pressure and the increased resistance to splenic blood outflow (14), although there is a relatively weak correlation between portal venous pressure and spleen size. |
| PubMedID- 20206401 | Relevance of the mtor signaling pathway in the pathophysiology of splenomegaly in rats with chronic portal hypertension. |
| PubMedID- 24718401 | splenomegaly has been associated with portal hypertension, with greater splenic enlargement resulting in more aggravated portal hypertension30. |
| PubMedID- 22372805 | Hepatoportal sclerosis (hps) is characterized by presinusoidal intrahepatic portal hypertension associated with splenomegaly and anemia in patients with non-cirrhotic liver. |
| PubMedID- 21162885 | The signs related to portal hypertension included splenomegaly (moderate or severe in all patients), hepatomegaly (mild or moderate in most of patients), shifting dullness positive and varices in abdominal wall. |
| PubMedID- 21499004 | As a result, portal hypertension associated with splenomegaly occurs in some cases. |
| PubMedID- 20852922 | At the time of presentation, portal hypertension with hepato-splenomegaly and oesophageal varices, as well as grade ii hepatic encephalopathy were diagnosed. |
| PubMedID- 26157903 | The splenomegaly can lead to left-sided portal hypertension. |
| PubMedID- 24987571 | [12345] portal hypertension is associated with splenomegaly and thrombocytopenia. |
| PubMedID- 20886427 | The patient was diagnosed with portal hypertension and due to marked splenomegaly, liver cirrhosis was suspected. |
| PubMedID- 22506126 | Transient elastography has also been used to determine spleen stiffness, using the hypothesis that splenomegaly resulting from portal hypertension causes changes in the spleen's density. |
| PubMedID- 25374706 | He had evidence of portal hypertension with an enlarged spleen and varices in the splenic hilum, collateral vessels within the abdominal walls, and a recanalized umbilical vein. |
| PubMedID- 24088733 | Conclusion: chronic hepatitis c virus infection and nsaid-associated splenomegaly because of portal hypertension are significant predictors of mortality in nonalcoholic patients presenting with upper gi bleeding. |
| PubMedID- 22792502 | In this way, s. mansoni and s. japonicum damage mainly the organs tributaries to the superior and inferior mesenteric vein which may result in several manifestations as colonic polyposis (s. mansoni), portal hypertension with haematemesis and splenomegaly (s. mansoni, s. japonicum). |
| PubMedID- 25962880 | The splenic vein was thrombosed and splenomegaly with left-sided portal hypertension was present. |
| PubMedID- 25501549 | Endothelial gab1 deficiency aggravates splenomegaly in portal hypertension independent of angiogenesis. |
| PubMedID- 24274743 | The animals show clear signs of portal hypertension with ascites, splenomegaly and splanchnic and systemic vasodilation, which are associated with decreased arterial pressure as well as intra- and extrahepatic angiogenesis[161]. |
| PubMedID- 26205377 | Recent research suggests that factors of splenomegaly in portal hypertension include not only spleen congestion, as traditionally thought, but also enlargement and hyperactivation of the splenic lymphoid tissue, as well as increased angiogenesis and fibrogenesis. |
| PubMedID- 24713723 | In the presence of portal hypertension with splenomegaly, the expected laboratory findings were leukopenia, thrombocytopenia. |
| PubMedID- 21566449 | Oxaliplatin-based chemotherapy may possibly produce hepatic sinusoidal dilation and induce splenomegaly owing to portal hypertension. |
| PubMedID- 25536638 | The natural history of pvt results in portal hypertension leading to splenomegaly and the formation of portosystemic collateral blood vessels and esophageal, gastric, duodenal, and jejunal varices. |
| PubMedID- 23754909 | In chronic cases, there is enlargement of the liver, mild jaundice, ascites, negative hepatojugular reflex, and splenomegaly with portal hypertension. |
| PubMedID- 23372427 | Ls, however, is usually regarded as less safe for patients with splenomegaly complicated by portal hypertension18. |
| PubMedID- 26329608 | A consequence of the liver fibrosis is portal hypertension, with associated splenomegaly, that can cause thrombocytopenia. |
Page: 1