PedAM

Pediatric Disease Annotations & Medicines

Disease	splenomegaly
Phenotype	C0020532\|hypersplenism
Sentences	11
PubMedID- 23617259	Objective: this study is aimed to evaluate the feasibility of laparoscopic splenectomy (ls) for massive splenomegaly in patients with hypersplenism secondary to portal hypertension and liver cirrhosis.
PubMedID- 24862308	splenomegaly, with or without hypersplenism, can also occur and can coexist with loss of function.
PubMedID- 20668714	splenomegaly is associated with hypersplenism leading to anemia and thrombocytopenia.
PubMedID- 24171010	Due to the extension of the fibrogenic cascade, focal biliary cirrhosis evolves into multilobular cirrhosis and its related complications such as splenomegaly with hypersplenism, esophageal or gastric varices, ascites and encephalopathy (33).
PubMedID- 20301287	Because lymphadenopathy and organomegaly often return once these agents are discontinued, immunosuppressive therapy is generally reserved for severe complications of lymphoproliferation (e.g., airway obstruction, significant hypersplenism associated with splenomegaly) and/or autoimmune manifestations.
PubMedID- 22227513	Progressive splenomegaly with pancytopenia (hypersplenism) is associated with epoprostenol use in poph.
PubMedID- 24396775	In the 1950's, splenectomy for splenomegaly with hypersplenism was the most common indication.
PubMedID- 25984660	splenomegaly with mild hypersplenism might be partly responsible for the unresolved thrombocytopenia.
PubMedID- 24255616	hypersplenism is a consequence of massive splenomegaly and is a common finding inchronic liver diseases.
PubMedID- 24791210	At the age of 8 years the patient was splenectomised due to giant splenomegaly, with hypersplenism and compression phenomena.
PubMedID- 21922871	Though mortality related to variceal bleeding is uncommon, morbidity due to massive splenomegaly with hypersplenism, growth failure, ectopic varices like rectal varices and portal biliopathy is significant.

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