PedAM
Pediatric Disease Annotations & Medicines
| Disease | splenomegaly |
| Phenotype | C0002871|anemia |
| Sentences | 15 |
| PubMedID- 22345918 | [3] some of the other mechanisms implicated in the causation of hematological abnormalities in disseminated tuberculosis include splenomegaly leading to hemolytic anemia and/or neutropenia, increased il-6 production causing thrombocytosis and cell-mediated autoimmune mechanisms causing neutropenia. |
| PubMedID- 26178367 | Dehydrated hereditary stomatocytosis (dhst) is an autosomal dominant congenital hemolytic anemia with moderate splenomegaly and often compensated hemolysis. |
| PubMedID- 26193228 | We present a case of a 52-year-old man hospitalized in july 2012 in the clinic of hematology of craiova, romania, having splenomegaly, leukocytosis with lymphocytosis, anemia and thrombocytopenia, without monocytopenia, which exposed, in the peripheral blood and bone marrow cells, intermediate morphology between hairy cells and prolymphocytes and immunophenotype of mature b-cell phenotype cd19, cd20, cd22, cd11c, cd103, low positive for cd25 and negative for cd3, diagnosed with hcl variant, with no response to conventional chemotherapy and interferon-alpha, an aggressive course of disease and a survival of less than a year from diagnosis. |
| PubMedID- 21445610 | Characteristic symptoms include splenomegaly with anemia and thrombocytopenia, hepatomegaly, and bone disease. |
| PubMedID- 21713221 | The disease is characterized by massive splenomegaly with anemia, preserved liver function and benign prognosis in a majority of patients. |
| PubMedID- 20670625 | We previously showed that ampkalpha1-/- mice develop moderate anemia associated with splenomegaly and high reticulocytosis. |
| PubMedID- 25910248 | Hypersplenism was defined as splenomegaly with thrombocytopenia, leukopenia, anemia and bone marrow aspiration revealed by biopsy. |
| PubMedID- 21976560 | The persistence of marked anemia in a patient with splenomegaly after a p. |
| PubMedID- 24816856 | The main inclusion criteria were a diagnosis of gd1 confirmed by deficient acid β-glucosidase activity and gaucher genotype, age 18 to 65 years, the presence of splenomegaly with anemia, and/or thrombocytopenia [16–18]. |
| PubMedID- 22084706 | Hypersplenism is arbitrarily defined as splenomegaly with anemia (when the transfusion requirements exceeds 250 ml/kg of packed red blood cells per year), thrombocytopenia (when the platelets level is less than 100,000/mm3), neutropenia (when the white blood cell count is less than 4,000/mm3) either singly or in combination. |
| PubMedID- 21468362 | Fatigue, moderate anemia, abdominal symptoms due to splenomegaly and lymphocytosis as incidental findings. |
| PubMedID- 25825577 | We discuss a case of massive splenomegaly who presented with symptomatic anemia and was found to have ma. |
| PubMedID- 22208203 | The clinical picture is characterized by mild to moderate anemia associated with jaundice, splenomegaly, and iron overload [3,4]. |
| PubMedID- 24252257 | Prominent symptoms at presentation include fatigue, weight loss, fever, and/or abdominal pain while signs include splenomegaly with associated anemia or thrombocytopenia while rarely presentation may be with splenic rupture [2]. |
| PubMedID- 22711990 | Klf3-deficient adults exhibit a mild compensated anemia, including enlarged spleens, increased red pulp, and a higher percentage of erythroid progenitors, together with elevated reticulocytes and abnormal erythrocytes in the peripheral blood. |
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