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PedAM

Pediatric Disease Annotations & Medicines




Disease splenomegaly
Phenotype C0002871|anaemia
Sentences 4
PubMedID- 21382177 Casp10 is known as a causative gene for autoimmune lymphoproliferative syndrome (alps) type iia, another childhood syndrome of lymphadenopathy and splenomegaly associated with autoimmune haemolytic anaemia and thrombocytopenia.
PubMedID- 23497273 Similarly the prevalence of anaemia in children with enlarged spleens was significantly (p < 0.01) higher than those with normal spleen (table 2).
PubMedID- 26017395 In malaria-endemic areas of papua new guinea (png), malarial anaemia associated with splenomegaly is a common clinical presentation.
PubMedID- 22540175 This may explain why concomitant severe malarial anaemia with spleen enlargement and cerebral malaria is relatively unusual with cerebral manifestations being more common in acute, fulminant infections and anaemia being more likely in chronic infections [27,76,128,129].

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