PedAM
Pediatric Disease Annotations & Medicines
| Disease | spinal cord injury |
| Phenotype | C0341747|detrusor sphincter dyssynergia |
| Sentences | 2 |
| PubMedID- 25042140 | Following use of botulinum toxin in the 1980s for the treatment of detrusor sphincter dyssynergia in patients with spinal cord injury (sci), the potential therapeutic value of this neurotoxin in urology has been the subject of much interest. |
| PubMedID- 22977301 | Btx-a in the urinary tract was first described by dykstra et al in 1988, who injected it into the external urinary sphincter to treat detrusor sphincter dyssynergia in patients with spinal cord injury.24 subsequently, schurch et al reported its use in the treatment of neurogenic detrusor overactivity in 12 patients with spinal cord injury.25 its use has since expanded in the management of lower urinary tract symptoms associated with idiopathic detrusor overactivity,26 bladder outflow obstruction,27 and painful bladder syndrome/interstitial cystitis. |
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