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PedAM

Pediatric Disease Annotations & Medicines




Disease smallpox
Phenotype C0042214|vaccinia
Sentences 11
PubMedID- 21933385 For example, in 2009 vigiv was used to treat a military smallpox vaccinee with progressive vaccinia [48].
PubMedID- 20566929 Conclusions: we present the first confirmed case of generalized vaccinia following immunization with the second-generation smallpox vaccine acam2000.
PubMedID- 23571177 Unintentional transfer of vaccinia virus associated with smallpox vaccines: acam2000((r)) compared with dryvax((r)).
PubMedID- 21499452 Results of the eind experience have been reported for the use of cmx001 to treat recurrent cmv (a case series involving three transplant patients who had failed valganciclovir therapy), adv infection (a case series of thirteen immunocompromised patients with a median age of 12 years, range 0.75 to 66, with disseminated adv infection) and progressive vaccinia (a single case with complications from smallpox vaccination).
PubMedID- 22258709 Successful vaccination against smallpox with conventional vaccinia virus is usually determined by the development of a vesicular skin lesion at the site of vaccinia inoculation, called a "take." although previous vaccination is known to be associated with attenuation of the take, the immunology that underlies a no-take in vaccinia-naive individuals is not well understood.
PubMedID- 20379365 Such studies were done in the mouse model of vaccinia since work with variola in humans is, of course, not possible.
PubMedID- 23760628 It was previously believed that the vaccinia vaccinal virus of the who smallpox global campaign, particularly vacv-ioc, had adapted to an unknown wild reservoir and was sporadically re-emerging by means of outbreaks in cattle and milkers.
PubMedID- 21931646 The methodology implemented in our study used a single in vitro vaccinia virus stimulation of pbmc derived from smallpox immunized subjects in order to expand and clone vaccinia specific t cells.
PubMedID- 25919588 Found that smallpox vaccination (vaccinia virus infection) in humans did not significantly alter levels of pre-existing igg to unrelated antigens, including tetanus and measles [29], suggesting that the accelerated declines in vaccine-specific igg observed in association with acute malaria in this study may be specific to plasmodium rather than a general feature of infection.
PubMedID- 21829313 Vaccination against smallpox is performed with the vaccinia virus, which has many antigenic structures in common with the smallpox agent.
PubMedID- 26239454 Ev is a rare, potentially life-threatening eruption that develops in predisposed individuals either after immunization for smallpox with live, attenuated vaccinia virus or physical contact with a recently vaccinated individual [48].

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