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PedAM

Pediatric Disease Annotations & Medicines




Disease sleep apnea
Phenotype C0878544|cardiomyopathy
Sentences 2
PubMedID- 25786209 Presently, myocardial changes associated with the obese state is referred to as obesity cardiomyopathy which is independent of hypertension, obstructive sleep apnea and coronary artery disease [3].mechanisms contributing to structural and functional changes in the heart due to obesity could include: altered cardiac metabolism, mitochondrial dysfunction, oxidative stress, impaired insulin signaling, inflammation, pressure/volume overload, sleep apnea, neurohumoral activation, cardiac fibrosis, and apoptosis [4].
PubMedID- 25634133 Hypertrophic cardiomyopathy associated with sleep apnea: serious implications and cogent management strategy.

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