PedAM
Pediatric Disease Annotations & Medicines
| Disease | sickle cell anemia |
| Phenotype | C0032269|pneumococcal infection |
| Sentences | 2 |
| PubMedID- 25375222 | Therefore, prophylactic penicillin regimens may be advisable for this population.objectives to assess the effects of prophylactic antibiotic regimens for preventing pneumococcal infection in children with sickle cell disease.search methods we searched the cochrane cystic fibrosis and genetic disorders group haemoglobinopathies trials register, which is comprised of references identified from comprehensive electronic database searches and handsearches of relevant journals and abstract books of conference proceedings.date of the most recent search: 26 june 2014.selection criteria all randomised or quasi-randomised controlled trials comparing prophylactic antibiotics to prevent pneumococcal infection in children with sickle cell disease with placebo, no treatment or a comparator drug.data collection and analysis both authors independently extracted data and assessed trial quality.main results five trials were identified by the initial search, of which three trials met the inclusion criteria. |
| PubMedID- 22972063 | Objectives: to assess the effects of prophylactic antibiotic regimens for preventing pneumococcal infection in children with sickle cell disease. |
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