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PedAM

Pediatric Disease Annotations & Medicines




Disease severe combined immunodeficiency
Phenotype C0376358|prostate cancer
Sentences 3
PubMedID- 23590837 After hplc purification, the grpr targeting ability of (111)in-dota-[aca-bn(7-14)]2 was assessed by microspect imaging in scid mice xenografted with the human prostate cancer cell line pc-3.
PubMedID- 23710216 Accumulating experimental evidence has demonstrated that pe inhibits tumor angiogenesis [12], delays the transition from androgen-dependent to androgen-independent phenotype, and induces apoptosis through a nuclear factor-kb-dependent mechanism in vitro and in tumor tissue excised from castrated severe combined immunodeficiency (scid) mice with los angeles prostate cancer-4 (lapc-4) human pca xenografts [13].
PubMedID- 23192356 Resveratrol worsens survival in scid mice with prostate cancer xenografts in a cell-line specific manner, through paradoxical effects on oncogenic pathways.

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