PedAM
Pediatric Disease Annotations & Medicines
| Disease | severe combined immunodeficiency |
| Phenotype | C0085110|severe combined immunodeficiency disease |
| Sentences | 5 |
| PubMedID- 23936793 | A mouse model of severe combined immunodeficiency disease (scid) [27] was developed in which conjoint implants of human fetal thymus and liver were placed under the kidney capsule with subsequent infection of hcmv [28]. |
| PubMedID- 21067584 | By means of a non-obese diabetic/severe combined immunodeficiency disease (nod/scid) xenotransplant assay in combination with specific cell surface markers (cd44+cd24-/low), cscs were enriched from metastatic and primary breast tumors and were shown to have the ability to reestablish tumor heterogeneity after transplantation [1]. |
| PubMedID- 20668627 | Ada deficiency is the major metabolic cause of severe combined immunodeficiency disease.31,32 ada is important for the development of the immune system in humans. |
| PubMedID- 25944695 | Six- to eight-week-old male cb.17/severe combined immunodeficiency disease (scid) mice were inoculated subcutaneously with 5 × 106 oci-ly7 tumor cells in 0.1 ml pbs for tumor development. |
| PubMedID- 21994645 | Approval of adagen® (pegademase) for the treatment of severe combined immunodeficiency disease (scid) by the u.s. fda in the early 1990s illustrated the potential for pegylation to significantly impact modern therapeutics. |
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