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PedAM

Pediatric Disease Annotations & Medicines




Disease severe combined immunodeficiency
Phenotype C0025202|melanoma
Sentences 8
PubMedID- 26078955 [27] reported that mcl-1 antisense oligonucleotides treatment of scid mice with melanoma subcutaneous tumors resulted in cancer sensitization to the chemotherapeutic drugs, accompanied by increased levels of apoptosis in tumor cells.
PubMedID- 22945357 We further performed in vivo experiments in the tumor model, where scid mice inoculated with b16 melanoma cells were transferred with con a-activated cd4+foxp3− t cells, together with or without anti-qa-1 antibody.
PubMedID- 21958294 Treatment of human melanoma-bearing scid or nsg mice with high doses of human t cells transduced with an hgp100/hla-a2-specific tcr did not result in antitumor responses irrespective of chemotherapeutic preconditioning.
PubMedID- 25961488 A single injection of scid mice implanted with human melanoma xenografts with 106 particles resulted in strong tumor regression.
PubMedID- 24905466 Moreover, administration of igfbp-3 in vivo to scid mice inoculated with human metastatic melanoma cells strongly reduced or completely inhibited tumor growth.
PubMedID- 23203681 Sex-dependent liver colonization of human melanoma in scid mice--role of host defense mechanisms.
PubMedID- 22622327 For this purpose a new model of scid-beige mice implanted with human melanoma was developed.
PubMedID- 19876915 scid mice engrafted with human melanoma were used to study esom administration effects on tumor growth and tumor ph by magnetic resonance spectroscopy (mrs).

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