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PedAM

Pediatric Disease Annotations & Medicines




Disease septicemia
Phenotype C0040034|thrombocytopenia
Sentences 21
PubMedID- 20530051 A difficult diagnosis case of prolonged thrombocytopenia with sepsis and disseminated intravascular coagulation.
PubMedID- 24575265 thrombocytopenia was associated with sepsis, intrauterine growth retardation sepsis, asphyxia, gdm, maternal hypertension and prematurity.
PubMedID- 25897412 In the two cases presented here, the presence of kikuchi-like lymphadenitis in the context of connective tissue disease produced a sepsis-like clinical picture, with thrombocytopenia and dic, which proved fatal.
PubMedID- 23166427 (23) reported that the presence of thrombocytopenia in patients with sepsis was associated with a relative risk of mortality of 1.7, and vanderschueren et al.
PubMedID- 23537039 Decreased levels have been observed in healthy volunteers following endotoxin infusion [23], in inflammatory diseases, and also in thrombocytopenia associated with severe sepsis [8,11,24].
PubMedID- 26276375 Objective: to examine the platelet recovering and anti-inflammatory effects of il-11 in the treatment of sepsis, accompanied with thrombocytopenia and to investigate the associated mechanisms via a case-control study.
PubMedID- 24800712 Results: the patient presented neonatal sepsis associated with significant leucopenia, thrombocytopenia and alteration of the coagulation profile.
PubMedID- 21805225 For example, thrombocytopenia in patients with sepsis confers an increased risk of bleeding [18].
PubMedID- 24521521 Undoubtedly, the etiology of thrombocytopenia in sepsis is multifactorial and includes microcirculatory and coagulation-associated effects.
PubMedID- 25535422 Hit, immune thrombocytopenia, dic due to sepsis are common.
PubMedID- 25986785 Discussion: to our knowledge, this is the first study to evaluate the safety and efficacy of recombinant human thrombopoietin among severe sepsis patients with thrombocytopenia in a varied population.
PubMedID- 23497478 They concluded that at least two patterns of platelet size changes could be possible in response to infection: an early rise in mpv in severe infection such as septicemia (may be associated with thrombocytopenia) and a later decrease in mpv with sustained or chronic or persisted bacterial infection (may be associated with thrombocytosis).
PubMedID- 25810916 The development of thrombocytopenia in patients with sepsis is secondary to various mechanisms.
PubMedID- 22529605 Peripheral platelet destruction is the mechanism for the thrombocytopenia in sepsis, with the evidence that endotoxin causes morphologic changes, platelet aggregation, and release of thromboplastic phosphatides (platelet factor iii) in vitro.
PubMedID- 26498205 As both platelets and red blood cells store and release s1p [35–37], thrombocytopenia and anemia in patients with sepsis may contribute to their low serum-s1p concentrations [38, 39].
PubMedID- 25471646 Initial leukopenia and thrombocytopenia was attributed to underlying sepsis and disseminated intravascular coagulation.
PubMedID- PMC4471329 thrombocytopenia is associated with sepsis severity and poor prognosis, and hyperactivated platelets probably contribute to microvascular thrombosis and organ failure.
PubMedID- 21422941 sepsis was the cause of significant thrombocytopenia after the first week of hospitalization.
PubMedID- 20487559 thrombocytopenia (mostly due to sepsis or hemodilution) is a very common laboratory finding, occurring in ~30% to 50% of patients in the medical icu [23].
PubMedID- 21244683 In 6 patients whose tbsa was over 30%, thrombocytopenia due to sepsis developed.
PubMedID- 24405656 Introduction: thrombocytopenia is prevalent in patients with severe sepsis, and it is associated with mortalities.

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