PedAM
Pediatric Disease Annotations & Medicines
| Disease | septicemia |
| Phenotype | C0032285|lung inflammation |
| Sentences | 3 |
| PubMedID- PMC3504804 | Thalidomide proved a promising immunomodulatory agent with a potential to modulate aggravated innate immune response observed during acute lung inflammation associated with pneumonia or sepsis caused by gram-negative bacterial infection. |
| PubMedID- 24265742 | Thus, the middle dose of endotoxin, 0.001 mg, resulted in cytokine levels similar to non-survivors of sepsis and was associated with significant lung inflammation and a 50% reduction in gfr. |
| PubMedID- 23117583 | We compared ros generation in wildtype mice and nadph oxidase-deficient p47(phox-/-) mice (2) in the following three models: 1) intratracheal administration of zymosan, a pro-inflammatory fungal cell wall-derived product that can activate nadph oxidase; 2) cecal ligation and puncture (clp), a model of intra-abdominal sepsis with secondary acute lung inflammation and injury; and 3) oral carbon tetrachloride (ccl4), a model of ros-dependent hepatic injury. |
Page: 1