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PedAM

Pediatric Disease Annotations & Medicines




Disease septicemia
Phenotype C0026846|muscle atrophy
Sentences 2
PubMedID- 20577146 sepsis-induced muscle atrophy is produced in part by decreased protein synthesis mediated by inhibition of mtor (mammalian target of rapamycin).
PubMedID- 25208653 Skeletal muscle atrophy during sepsis, immobilization, and chronic diseases is characterized by an increase in expression and activity of the muscle-specific ubiquitin 3 ligases atrogin-1 and murf-1.

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