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PedAM

Pediatric Disease Annotations & Medicines




Disease septicemia
Phenotype C0025229|melioidosis
Sentences 17
PubMedID- 25370187 To investigate fsap activation in patients suffering from burkholderia pseudomallei infection (melioidosis), an important cause of gram-negative sepsis in southeast asia.
PubMedID- 21110886 Acute forms of melioidosis that lead to sepsis, multiple organ failure and death are thought to result from an uncontrolled inflammatory reaction that ultimately leads to excessive inflammation [7] and eventually tissue injury in the b. pseudomallei-infected host.
PubMedID- 23508691 However, in human melioidosis patients with sepsis, increased tnf-α production is thought to actually be associated with higher mortality rates (suputtamongkol et al., 1992).
PubMedID- 23951382 Acute melioidosis with septicemia, which is transmitted through various routes of infection, is the most severe for humans [5] and animals [3], [6]–[10].
PubMedID- 25943405 In northeastern thailand, melioidosis accounts for 20% of community-acquired sepsis, with a case-mortality rate of 30–50% [3,4].
PubMedID- 21791666 The gram-negative bacterium burkholderia pseudomallei is the causative agent of melioidosis, a major cause of lethal sepsis and morbidity in endemic areas of southeast asia and a potential bioterrorism threat.
PubMedID- 23675544 In human trials, complementary use of granulocyte colony-stimulating factor improved the duration of survival for melioidosis patients with severe sepsis but did not decrease mortality rates [5].
PubMedID- 24392083 Common tlr1 genetic variation is not associated with death from melioidosis, a common cause of sepsis in rural thailand.
PubMedID- 24618705 Cutaneous melioidosis without sepsis occurs as the primary presentation in 13% of australian cases [3], mostly in those with no identified risk factors and commonly in children; furthermore, fatalities have yet to be documented in this cohort [29].
PubMedID- 20142364 The gram-negative bacterium burkholderia pseudomallei is able to survive and replicate within leukocytes and causes melioidosis, an important cause of pneumonia-derived community-acquired sepsis in southeast asia.
PubMedID- 24285369 In northeast thailand, melioidosis accounts for 20% of cases of community-acquired septicemia with a mortality rate of 50%56.
PubMedID- 24239704 In this study we aimed to investigate the role of par-1 during melioidosis, a common cause of (pneumo)sepsis in southeast asia in a murine model of intranasal inoculation of the causative pathogen burkholderia (b.) pseudomallei.
PubMedID- 25191391 We report a case of pulmonary melioidosis associated with septicemia in a 69 year-old diabetic man during a trip to southeast asia.
PubMedID- 23278969 We report a rare case of pleuro-pulmonary melioidosis with septicemia in a renal transplant recipient to highlight the potential risk of acquiring this infection in at-risk patients living in, or visiting, regions that are endemic for melioidosis, and to convey the importance of its early diagnosis and specific treatment.
PubMedID- 22448290 This intracellular gram negative bacteria is endemic throughout northern australia and parts of southeast asia, where as much as 20% of septicemia is attributed to melioidosis [1], [2].
PubMedID- 22007185 melioidosis accounts for 20% of all community-acquired septicemias in northeast thailand (chaowagul et al., 1989) and 32% of community-acquired bacteremic pneumonia and 6% of all bacteremias in northern australia (douglas et al., 2004).
PubMedID- 26215706 We studied the role of nets in burkholderia pseudomallei infection (melioidosis), an important cause of gram-negative sepsis in southeast asia.

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